BRD-K09602097_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

172 genes differentially expressed following the BRD-K09602097_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADA adenosine deaminase
ADM adrenomedullin
AHNAK AHNAK nucleoprotein
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDOB aldolase B, fructose-bisphosphate
APLP2 amyloid beta (A4) precursor-like protein 2
ATP10D ATPase, class V, type 10D
BASP1 brain abundant, membrane attached signal protein 1
BEX4 brain expressed, X-linked 4
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAPG capping protein (actin filament), gelsolin-like
CAPN2 calpain 2, (m/II) large subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC81 coiled-coil domain containing 81
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK14 cyclin-dependent kinase 14
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLIC3 chloride intracellular channel 3
CLIP1 CAP-GLY domain containing linker protein 1
COLEC12 collectin sub-family member 12
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL11 chemokine (C-X-C motif) ligand 11
DFNA5 deafness, autosomal dominant 5
DSG2 desmoglein 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENO2 enolase 2 (gamma, neuronal)
FABP6 fatty acid binding protein 6, ileal
FAM129A family with sequence similarity 129, member A
FBLN1 fibulin 1
FHL1 four and a half LIM domains 1
FRY furry homolog (Drosophila)
GATA3 GATA binding protein 3
GLRX glutaredoxin (thioltransferase)
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNLY granulysin
HIST1H1C histone cluster 1, H1c
HOMER3 homer scaffolding protein 3
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP5 insulin-like growth factor binding protein 5
IL13RA1 interleukin 13 receptor, alpha 1
IQGAP1 IQ motif containing GTPase activating protein 1
KRT7 keratin 7, type II
LAMA4 laminin, alpha 4
LGALS1 lectin, galactoside-binding, soluble, 1
MAOA monoamine oxidase A
MGP matrix Gla protein
MMP12 matrix metallopeptidase 12
MOCOS molybdenum cofactor sulfurase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MZB1 marginal zone B and B1 cell-specific protein
NT5E 5'-nucleotidase, ecto (CD73)
P3H2 prolyl 3-hydroxylase 2
PBX3 pre-B-cell leukemia homeobox 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PEX11A peroxisomal biogenesis factor 11 alpha
PPAP2B phosphatidic acid phosphatase type 2B
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB31 RAB31, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHOB ras homolog family member B
SCGB2A2 secretoglobin, family 2A, member 2
SEC14L1 SEC14-like 1 (S. cerevisiae)
SFRP1 secreted frizzled-related protein 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SOCS2 suppressor of cytokine signaling 2
SPARCL1 SPARC-like 1 (hevin)
SPTSSA serine palmitoyltransferase, small subunit A
STC1 stanniocalcin 1
STS steroid sulfatase (microsomal), isozyme S
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIM2 tripartite motif containing 2
TXNL4B thioredoxin-like 4B
WNT5A wingless-type MMTV integration site family, member 5A
YPEL5 yippee-like 5 (Drosophila)
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ASPN asporin
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
BIN1 bridging integrator 1
BPHL biphenyl hydrolase-like (serine hydrolase)
CACYBP calcyclin binding protein
CALML3 calmodulin-like 3
CBX3 chromobox homolog 3
CD24 CD24 molecule
COX17 COX17 cytochrome c oxidase copper chaperone
COX5A cytochrome c oxidase subunit Va
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DLD dihydrolipoamide dehydrogenase
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM162A family with sequence similarity 162, member A
FCGBP Fc fragment of IgG binding protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GGCT gamma-glutamylcyclotransferase
GNAS GNAS complex locus
GPX2 glutathione peroxidase 2
GTPBP8 GTP-binding protein 8 (putative)
HAMP hepcidin antimicrobial peptide
HN1 hematological and neurological expressed 1
HOXA10 homeobox A10
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPA1A heat shock 70kDa protein 1A
IGHM immunoglobulin heavy constant mu
KRT10 keratin 10, type I
KRT14 keratin 14, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LPL lipoprotein lipase
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTB lymphotoxin beta (TNF superfamily, member 3)
LUC7L3 LUC7-like 3 (S. cerevisiae)
LUM lumican
LYPD1 LY6/PLAUR domain containing 1
LYPLA1 lysophospholipase I
MARCKS myristoylated alanine-rich protein kinase C substrate
MATN2 matrilin 2
MBNL1 muscleblind-like splicing regulator 1
MBP myelin basic protein
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MFSD10 major facilitator superfamily domain containing 10
MLEC malectin
MOXD1 monooxygenase, DBH-like 1
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
NUTF2 nuclear transport factor 2
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PKN2 protein kinase N2
PLK1 polo-like kinase 1
PPA1 pyrophosphatase (inorganic) 1
PRDX2 peroxiredoxin 2
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RBM3 RNA binding motif (RNP1, RRM) protein 3
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RNASET2 ribonuclease T2
RPA3 replication protein A3, 14kDa
RPL26L1 ribosomal protein L26-like 1
RPL27A ribosomal protein L27a
RPL36AL ribosomal protein L36a-like
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
RPS21 ribosomal protein S21
SEC61G Sec61 gamma subunit
SLIRP SRA stem-loop interacting RNA binding protein
SLPI secretory leukocyte peptidase inhibitor
SNRPF small nuclear ribonucleoprotein polypeptide F
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
SRPX sushi-repeat containing protein, X-linked
SSR1 signal sequence receptor, alpha
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TSPAN3 tetraspanin 3
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
USP22 ubiquitin specific peptidase 22
WDR61 WD repeat domain 61