BRD-K09602097_-666_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K09602097_-666_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL4C ADP-ribosylation factor-like 4C
C3ORF14 chromosome 3 open reading frame 14
CCND2 cyclin D2
CD9 CD9 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CENPU centromere protein U
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
CPA3 carboxypeptidase A3 (mast cell)
DES desmin
DLK1 delta-like 1 homolog (Drosophila)
EREG epiregulin
FAM129A family with sequence similarity 129, member A
FGL2 fibrinogen-like 2
FRY furry homolog (Drosophila)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H1C histone cluster 1, H1c
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IPO13 importin 13
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT18 keratin 18, type I
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MEIS2 Meis homeobox 2
NEB nebulin
NR1H2 nuclear receptor subfamily 1, group H, member 2
P3H2 prolyl 3-hydroxylase 2
PLK2 polo-like kinase 2
PLS1 plastin 1
RAB25 RAB25, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RTN2 reticulon 2
SFRP1 secreted frizzled-related protein 1
TACSTD2 tumor-associated calcium signal transducer 2
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPPP3 tubulin polymerization-promoting protein family member 3
UBE3B ubiquitin protein ligase E3B
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ACLY ATP citrate lyase
ACTA2 actin, alpha 2, smooth muscle, aorta
ALDOA aldolase A, fructose-bisphosphate
ALDOC aldolase C, fructose-bisphosphate
APOE apolipoprotein E
BAALC brain and acute leukemia, cytoplasmic
BST2 bone marrow stromal cell antigen 2
CA12 carbonic anhydrase XII
CD59 CD59 molecule, complement regulatory protein
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTGF connective tissue growth factor
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYTL1 cytokine-like 1
DCN decorin
DLC1 DLC1 Rho GTPase activating protein
DLD dihydrolipoamide dehydrogenase
DUSP1 dual specificity phosphatase 1
EBP emopamil binding protein (sterol isomerase)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM162A family with sequence similarity 162, member A
FASN fatty acid synthase
GNAS GNAS complex locus
HSPD1 heat shock 60kDa protein 1 (chaperonin)
LOX lysyl oxidase
LPL lipoprotein lipase
MARCKSL1 MARCKS-like 1
MYLK myosin light chain kinase
NR2F6 nuclear receptor subfamily 2, group F, member 6
POSTN periostin, osteoblast specific factor
QDPR quinoid dihydropteridine reductase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP4 retinol binding protein 4, plasma
S100B S100 calcium binding protein B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SRPX sushi-repeat containing protein, X-linked
TAGLN transgelin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TF transferrin
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TSPAN3 tetraspanin 3
VAT1 vesicle amine transport 1