BRD-K09602097_-666_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

135 genes differentially expressed following the BRD-K09602097_-666_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADI1 acireductone dioxygenase 1
ARG2 arginase 2
ASCL1 achaete-scute family bHLH transcription factor 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BEX4 brain expressed, X-linked 4
C1QA complement component 1, q subcomponent, A chain
CADM1 cell adhesion molecule 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD14 CD14 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CKB creatine kinase, brain
COL11A1 collagen, type XI, alpha 1
COL9A2 collagen, type IX, alpha 2
CPB1 carboxypeptidase B1 (tissue)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCN decorin
DENND1B DENN/MADD domain containing 1B
DLK1 delta-like 1 homolog (Drosophila)
EDN1 endothelin 1
ESR1 estrogen receptor 1
EXOSC4 exosome component 4
FAM198B family with sequence similarity 198, member B
FCGBP Fc fragment of IgG binding protein
FTH1 ferritin, heavy polypeptide 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HYOU1 hypoxia up-regulated 1
JCHAIN joining chain of multimeric IgA and IgM
KLK5 kallikrein-related peptidase 5
KRT19 keratin 19, type I
KRT23 keratin 23, type I
LCN2 lipocalin 2
LGALS8 lectin, galactoside-binding, soluble, 8
LTF lactotransferrin
LUM lumican
MEIS2 Meis homeobox 2
MMP2 matrix metallopeptidase 2
MPZL2 myelin protein zero-like 2
MUC16 mucin 16, cell surface associated
MXRA5 matrix-remodelling associated 5
NR4A2 nuclear receptor subfamily 4, group A, member 2
NXN nucleoredoxin
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCP4 Purkinje cell protein 4
PEG10 paternally expressed 10
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLK2 polo-like kinase 2
PRKX protein kinase, X-linked
RAB25 RAB25, member RAS oncogene family
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SC5D sterol-C5-desaturase
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SNX7 sorting nexin 7
SULF1 sulfatase 1
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TAGLN transgelin
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM30B transmembrane protein 30B
TNNC1 troponin C type 1 (slow)
TPD52L1 tumor protein D52-like 1
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADIRF adipogenesis regulatory factor
AHNAK2 AHNAK nucleoprotein 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AQP3 aquaporin 3 (Gill blood group)
BASP1 brain abundant, membrane attached signal protein 1
C16ORF45 chromosome 16 open reading frame 45
C1S complement component 1, s subcomponent
C8ORF4 chromosome 8 open reading frame 4
CH25H cholesterol 25-hydroxylase
CTSC cathepsin C
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL5 chemokine (C-X-C motif) ligand 5
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
EPS8 epidermal growth factor receptor pathway substrate 8
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FASN fatty acid synthase
FGFR4 fibroblast growth factor receptor 4
FKBP11 FK506 binding protein 11, 19 kDa
FLRT3 fibronectin leucine rich transmembrane protein 3
FOLR1 folate receptor 1 (adult)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GSTA4 glutathione S-transferase alpha 4
HMG20B high mobility group 20B
HOXC6 homeobox C6
HTRA1 HtrA serine peptidase 1
IFI27 interferon, alpha-inducible protein 27
JARID2 jumonji, AT rich interactive domain 2
KLF4 Kruppel-like factor 4 (gut)
KLHL9 kelch-like family member 9
LAMC1 laminin, gamma 1 (formerly LAMB2)
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
NFIB nuclear factor I/B
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLBD1 phospholipase B domain containing 1
PPARG peroxisome proliferator-activated receptor gamma
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
REG3A regenerating islet-derived 3 alpha
RNF167 ring finger protein 167
SASH1 SAM and SH3 domain containing 1
SELL selectin L
SKAP2 src kinase associated phosphoprotein 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLIRP SRA stem-loop interacting RNA binding protein
SMAD3 SMAD family member 3
SORBS3 sorbin and SH3 domain containing 3
SPATS2L spermatogenesis associated, serine-rich 2-like
SPTBN1 spectrin, beta, non-erythrocytic 1
STOM stomatin
STX1A syntaxin 1A (brain)
TBC1D31 TBC1 domain family, member 31
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
TIMP4 TIMP metallopeptidase inhibitor 4
TMEM100 transmembrane protein 100
TNC tenascin C
TRIP6 thyroid hormone receptor interactor 6
TSPAN3 tetraspanin 3
XPO7 exportin 7
ZBTB20 zinc finger and BTB domain containing 20