BRD-K09549677_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K09549677_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOC aldolase C, fructose-bisphosphate
APOD apolipoprotein D
AREG amphiregulin
ASNS asparagine synthetase (glutamine-hydrolyzing)
BTG1 B-cell translocation gene 1, anti-proliferative
CD40 CD40 molecule, TNF receptor superfamily member 5
CD8A CD8a molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP57 centrosomal protein 57kDa
CHGB chromogranin B
CPA3 carboxypeptidase A3 (mast cell)
CPB1 carboxypeptidase B1 (tissue)
CST1 cystatin SN
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
DUSP4 dual specificity phosphatase 4
FAM129A family with sequence similarity 129, member A
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
GRN granulin
H1F0 H1 histone family, member 0
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HOPX HOP homeobox
IFI27 interferon, alpha-inducible protein 27
IL32 interleukin 32
INSIG1 insulin induced gene 1
IRF6 interferon regulatory factor 6
ISG20 interferon stimulated exonuclease gene 20kDa
KIF5C kinesin family member 5C
KLF6 Kruppel-like factor 6
KRT23 keratin 23, type I
LPIN1 lipin 1
PDGFD platelet derived growth factor D
PHLDA1 pleckstrin homology-like domain, family A, member 1
RABAC1 Rab acceptor 1 (prenylated)
RAP1GAP RAP1 GTPase activating protein
RFTN1 raftlin, lipid raft linker 1
RHOQ ras homolog family member Q
RND3 Rho family GTPase 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPRED2 sprouty-related, EVH1 domain containing 2
SQLE squalene epoxidase
TFF3 trefoil factor 3 (intestinal)
THBS2 thrombospondin 2
TIMP1 TIMP metallopeptidase inhibitor 1
TRIM2 tripartite motif containing 2
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
VEGFA vascular endothelial growth factor A
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATAD2 ATPase family, AAA domain containing 2
AURKA aurora kinase A
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCNA2 cyclin A2
CCNB2 cyclin B2
CDCA3 cell division cycle associated 3
CDK1 cyclin-dependent kinase 1
CENPA centromere protein A
CSE1L CSE1 chromosome segregation 1-like (yeast)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EIF1AX eukaryotic translation initiation factor 1A, X-linked
FOXM1 forkhead box M1
H2AFX H2A histone family, member X
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LAPTM4B lysosomal protein transmembrane 4 beta
NUP98 nucleoporin 98kDa
ODC1 ornithine decarboxylase 1
PBK PDZ binding kinase
PLAC8 placenta-specific 8
PLK1 polo-like kinase 1
POSTN periostin, osteoblast specific factor
PTTG1 pituitary tumor-transforming 1
RACGAP1 Rac GTPase activating protein 1
SPDL1 spindle apparatus coiled-coil protein 1
TACC3 transforming, acidic coiled-coil containing protein 3
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
ZWINT ZW10 interacting kinetochore protein