BRD-K09549677_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

33 genes differentially expressed following the BRD-K09549677_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AARS alanyl-tRNA synthetase
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
BTG1 B-cell translocation gene 1, anti-proliferative
CCNG2 cyclin G2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DPYSL2 dihydropyrimidinase-like 2
F13A1 coagulation factor XIII, A1 polypeptide
FCGBP Fc fragment of IgG binding protein
GLRX glutaredoxin (thioltransferase)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IL6ST interleukin 6 signal transducer
LINC00341 long intergenic non-protein coding RNA 341
LMO4 LIM domain only 4
MBNL2 muscleblind-like splicing regulator 2
MKNK2 MAP kinase interacting serine/threonine kinase 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUCB2 nucleobindin 2
NUPR1 nuclear protein, transcriptional regulator, 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PSAT1 phosphoserine aminotransferase 1
PSPH phosphoserine phosphatase
RHOBTB3 Rho-related BTB domain containing 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
VEGFA vascular endothelial growth factor A
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
CSRP1 cysteine and glycine-rich protein 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GBP1 guanylate binding protein 1, interferon-inducible
NEFH neurofilament, heavy polypeptide
SRSF7 serine/arginine-rich splicing factor 7