BRD-K09537769_NU-7026_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K09537769_NU-7026_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
CALR calreticulin
CLIC3 chloride intracellular channel 3
CPE carboxypeptidase E
FAIM Fas apoptotic inhibitory molecule
FAM198B family with sequence similarity 198, member B
FPGS folylpolyglutamate synthase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HOPX HOP homeobox
HOXB2 homeobox B2
HOXB6 homeobox B6
METTL7A methyltransferase like 7A
MYOF myoferlin
PDE4B phosphodiesterase 4B, cAMP-specific
POSTN periostin, osteoblast specific factor
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSAT1 phosphoserine aminotransferase 1
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RAI14 retinoic acid induced 14
RGS5 regulator of G-protein signaling 5
SARS seryl-tRNA synthetase
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC38A1 solute carrier family 38, member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNN stannin
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX11 SRY (sex determining region Y)-box 11
TBX3 T-box 3
TCF4 transcription factor 4
TLR4 toll-like receptor 4
TRIM2 tripartite motif containing 2
VCAN versican
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT5A wingless-type MMTV integration site family, member 5A
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
BACE2 beta-site APP-cleaving enzyme 2
C2CD5 C2 calcium-dependent domain containing 5
C8ORF4 chromosome 8 open reading frame 4
CCDC92 coiled-coil domain containing 92
CHI3L2 chitinase 3-like 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EFCAB14 EF-hand calcium binding domain 14
ENO2 enolase 2 (gamma, neuronal)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FOLR1 folate receptor 1 (adult)
FXYD2 FXYD domain containing ion transport regulator 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
HLTF helicase-like transcription factor
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
LAPTM4B lysosomal protein transmembrane 4 beta
MCAM melanoma cell adhesion molecule
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
RBPMS RNA binding protein with multiple splicing
SIK1 salt-inducible kinase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
TESC tescalcin
UGCG UDP-glucose ceramide glucosyltransferase