BRD-K09416995_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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38 genes differentially expressed following the BRD-K09416995_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
AGR2 anterior gradient 2
ALDOC aldolase C, fructose-bisphosphate
ALOX5 arachidonate 5-lipoxygenase
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CCNA1 cyclin A1
CRABP2 cellular retinoic acid binding protein 2
CRIP1 cysteine-rich protein 1 (intestinal)
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DYNLT3 dynein, light chain, Tctex-type 3
ENO2 enolase 2 (gamma, neuronal)
ESR1 estrogen receptor 1
FASN fatty acid synthase
GREB1 growth regulation by estrogen in breast cancer 1
HEPH hephaestin
HIST2H2BE histone cluster 2, H2be
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IER3 immediate early response 3
INSIG1 insulin induced gene 1
KLK6 kallikrein-related peptidase 6
LDLR low density lipoprotein receptor
MYRF myelin regulatory factor
PLA2G16 phospholipase A2, group XVI
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQLE squalene epoxidase
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TPPP3 tubulin polymerization-promoting protein family member 3
TST thiosulfate sulfurtransferase (rhodanese)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)

decreased expression

Symbol Name
CADM1 cell adhesion molecule 1
CDK6 cyclin-dependent kinase 6
FBN2 fibrillin 2
HSPA8 heat shock 70kDa protein 8
POSTN periostin, osteoblast specific factor