BRD-K09186807_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K09186807_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACP6 acid phosphatase 6, lysophosphatidic
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
BHLHE41 basic helix-loop-helix family, member e41
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCNG2 cyclin G2
CD9 CD9 molecule
CDK19 cyclin-dependent kinase 19
CFB complement factor B
ERBB2 erb-b2 receptor tyrosine kinase 2
H1F0 H1 histone family, member 0
HBP1 HMG-box transcription factor 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
KRT19 keratin 19, type I
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEBL nebulette
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THBS2 thrombospondin 2
TRIP6 thyroid hormone receptor interactor 6
VIM vimentin
YBX3 Y box binding protein 3

decreased expression

Symbol Name
ATF5 activating transcription factor 5
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCDC86 coiled-coil domain containing 86
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFNB2 ephrin-B2
EPCAM epithelial cell adhesion molecule
EPHA3 EPH receptor A3
FTH1 ferritin, heavy polypeptide 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
HSPH1 heat shock 105kDa/110kDa protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JMJD6 jumonji domain containing 6
KCTD12 potassium channel tetramerization domain containing 12
KCTD5 potassium channel tetramerization domain containing 5
LDHB lactate dehydrogenase B
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)