BRD-K09186807_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K09186807_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK AHNAK nucleoprotein
AIM1 absent in melanoma 1
BID BH3 interacting domain death agonist
C1ORF115 chromosome 1 open reading frame 115
CAPG capping protein (actin filament), gelsolin-like
CCNG2 cyclin G2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK19 cyclin-dependent kinase 19
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CPM carboxypeptidase M
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGR3 early growth response 3
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EZR ezrin
F13A1 coagulation factor XIII, A1 polypeptide
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GREB1 growth regulation by estrogen in breast cancer 1
GSTM3 glutathione S-transferase mu 3 (brain)
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KDM5D lysine (K)-specific demethylase 5D
LINC00341 long intergenic non-protein coding RNA 341
LMO3 LIM domain only 3 (rhombotin-like 2)
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAOA monoamine oxidase A
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MEF2C myocyte enhancer factor 2C
MKNK1 MAP kinase interacting serine/threonine kinase 1
MXI1 MAX interactor 1, dimerization protein
NRGN neurogranin (protein kinase C substrate, RC3)
NUPR1 nuclear protein, transcriptional regulator, 1
PDE10A phosphodiesterase 10A
PEX11A peroxisomal biogenesis factor 11 alpha
RNASET2 ribonuclease T2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SORBS2 sorbin and SH3 domain containing 2
SRGN serglycin
STAR steroidogenic acute regulatory protein
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TLR4 toll-like receptor 4
TPD52L1 tumor protein D52-like 1
TXNIP thioredoxin interacting protein
VNN1 vanin 1
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
C11ORF24 chromosome 11 open reading frame 24
CAT catalase
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CKAP4 cytoskeleton-associated protein 4
CRY1 cryptochrome circadian clock 1
CTSK cathepsin K
CXCL14 chemokine (C-X-C motif) ligand 14
CYTL1 cytokine-like 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DLC1 DLC1 Rho GTPase activating protein
ECM1 extracellular matrix protein 1
EIF1AX eukaryotic translation initiation factor 1A, X-linked
FAM134B family with sequence similarity 134, member B
FBXL12 F-box and leucine-rich repeat protein 12
GRWD1 glutamate-rich WD repeat containing 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP6 insulin-like growth factor binding protein 6
IL7R interleukin 7 receptor
LPAR1 lysophosphatidic acid receptor 1
MX1 MX dynamin-like GTPase 1
NEBL nebulette
NOLC1 nucleolar and coiled-body phosphoprotein 1
NRG1 neuregulin 1
NRIP1 nuclear receptor interacting protein 1
OAT ornithine aminotransferase
ODC1 ornithine decarboxylase 1
PEG10 paternally expressed 10
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRDX2 peroxiredoxin 2
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SNAI2 snail family zinc finger 2
TSC22D2 TSC22 domain family, member 2
TSPAN3 tetraspanin 3
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TWIST1 twist family bHLH transcription factor 1
UFM1 ubiquitin-fold modifier 1
ZIC1 Zic family member 1