BRD-K08878345_MLS-0075347.0001_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

106 genes differentially expressed following the BRD-K08878345_MLS-0075347.0001_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADCK3 aarF domain containing kinase 3
AHNAK2 AHNAK nucleoprotein 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATP9A ATPase, class II, type 9A
CHRDL1 chordin-like 1
CLU clusterin
CST3 cystatin C
CSTA cystatin A (stefin A)
CTTN cortactin
DHRS3 dehydrogenase/reductase (SDR family) member 3
DPT dermatopontin
F13A1 coagulation factor XIII, A1 polypeptide
FHL1 four and a half LIM domains 1
HPCAL1 hippocalcin-like 1
INSIG1 insulin induced gene 1
ISLR immunoglobulin superfamily containing leucine-rich repeat
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KRT18 keratin 18, type I
LCN2 lipocalin 2
LPIN1 lipin 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MLPH melanophilin
MT1E metallothionein 1E
NQO1 NAD(P)H dehydrogenase, quinone 1
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PHYH phytanoyl-CoA 2-hydroxylase
PITX1 paired-like homeodomain 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAC8 placenta-specific 8
PPL periplakin
PRDX2 peroxiredoxin 2
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PYCR1 pyrroline-5-carboxylate reductase 1
RAB2A RAB2A, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAP1GAP RAP1 GTPase activating protein
RBP4 retinol binding protein 4, plasma
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A11 S100 calcium binding protein A11
S100A14 S100 calcium binding protein A14
SELENBP1 selenium binding protein 1
SFN stratifin
STEAP3 STEAP family member 3, metalloreductase
TACSTD2 tumor-associated calcium signal transducer 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADM adrenomedullin
C3ORF14 chromosome 3 open reading frame 14
CD177 CD177 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CDK2 cyclin-dependent kinase 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYBA cytochrome b-245, alpha polypeptide
DCT dopachrome tautomerase
DPP4 dipeptidyl-peptidase 4
EDNRB endothelin receptor type B
FN1 fibronectin 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GOLGA8A golgin A8 family, member A
GREM1 gremlin 1, DAN family BMP antagonist
HIST1H2BG histone cluster 1, H2bg
LOC100272216 uncharacterized LOC100272216
LPCAT1 lysophosphatidylcholine acyltransferase 1
LUM lumican
LXN latexin
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NID2 nidogen 2 (osteonidogen)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PBX3 pre-B-cell leukemia homeobox 3
PDE4B phosphodiesterase 4B, cAMP-specific
PLAGL1 pleiomorphic adenoma gene-like 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRAME preferentially expressed antigen in melanoma
PTHLH parathyroid hormone-like hormone
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RTN2 reticulon 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
STOM stomatin
SWAP70 SWAP switching B-cell complex 70kDa subunit
TARBP1 TAR (HIV-1) RNA binding protein 1
TARP TCR gamma alternate reading frame protein
TFPI2 tissue factor pathway inhibitor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM255A transmembrane protein 255A
TMEM47 transmembrane protein 47
TMSB15A thymosin beta 15a
TPD52 tumor protein D52
UBE2A ubiquitin-conjugating enzyme E2A
XIST X inactive specific transcript (non-protein coding)