BRD-K08799216_pelitinib_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K08799216_pelitinib_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ASCL1 achaete-scute family bHLH transcription factor 1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CAPG capping protein (actin filament), gelsolin-like
CD9 CD9 molecule
CYB561 cytochrome b561
DDIT4 DNA-damage-inducible transcript 4
EAPP E2F-associated phosphoprotein
ECI2 enoyl-CoA delta isomerase 2
FOXC1 forkhead box C1
GPM6B glycoprotein M6B
GSTA1 glutathione S-transferase alpha 1
GTPBP1 GTP binding protein 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
JAM3 junctional adhesion molecule 3
KLF9 Kruppel-like factor 9
MME membrane metallo-endopeptidase
MT1M metallothionein 1M
MYO6 myosin VI
RAB11FIP1 RAB11 family interacting protein 1 (class I)
SC5D sterol-C5-desaturase
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SIRT3 sirtuin 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VAMP8 vesicle-associated membrane protein 8
YBX3 Y box binding protein 3

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGAP29 Rho GTPase activating protein 29
AVL9 AVL9 homolog (S. cerevisiase)
BCHE butyrylcholinesterase
BCL2A1 BCL2-related protein A1
BMI1 BMI1 proto-oncogene, polycomb ring finger
C5AR1 complement component 5a receptor 1
CD36 CD36 molecule (thrombospondin receptor)
CSTA cystatin A (stefin A)
CXADR coxsackie virus and adenovirus receptor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GRB7 growth factor receptor-bound protein 7
GREM1 gremlin 1, DAN family BMP antagonist
HIPK1 homeodomain interacting protein kinase 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSPA1A heat shock 70kDa protein 1A
JUN jun proto-oncogene
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MARCKS myristoylated alanine-rich protein kinase C substrate
NBN nibrin
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLXNC1 plexin C1
PPAP2C phosphatidic acid phosphatase type 2C
PRKCH protein kinase C, eta
PTDSS1 phosphatidylserine synthase 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBP1 retinol binding protein 1, cellular
RPS11 ribosomal protein S11
SAMD4A sterile alpha motif domain containing 4A
SFRP1 secreted frizzled-related protein 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SNAP25 synaptosomal-associated protein, 25kDa
STC1 stanniocalcin 1
XIST X inactive specific transcript (non-protein coding)