BRD-K08799216_pelitinib_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K08799216_pelitinib_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP8 A kinase (PRKA) anchor protein 8
C6ORF62 chromosome 6 open reading frame 62
COL10A1 collagen, type X, alpha 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
PEBP1 phosphatidylethanolamine binding protein 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
REG1A regenerating islet-derived 1 alpha
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SIK1 salt-inducible kinase 1

decreased expression

Symbol Name
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DCLK1 doublecortin-like kinase 1
GDF15 growth differentiation factor 15
GEM GTP binding protein overexpressed in skeletal muscle
HES1 hes family bHLH transcription factor 1
HOXA10 homeobox A10
IER3 immediate early response 3
LUM lumican
MET MET proto-oncogene, receptor tyrosine kinase
NPY1R neuropeptide Y receptor Y1
PHLDA2 pleckstrin homology-like domain, family A, member 2
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
SLC16A6 solute carrier family 16, member 6
TES testin LIM domain protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TIMP1 TIMP metallopeptidase inhibitor 1
ZFP36 ZFP36 ring finger protein