BRD-K08799216_pelitinib_BT20_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K08799216_pelitinib_BT20_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ABHD4 abhydrolase domain containing 4
AZU1 azurocidin 1
CAMP cathelicidin antimicrobial peptide
CCPG1 cell cycle progression 1
CFB complement factor B
CTH cystathionine gamma-lyase
CXADR coxsackie virus and adenovirus receptor
ELANE elastase, neutrophil expressed
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLUL glutamate-ammonia ligase
GUSBP11 glucuronidase, beta pseudogene 11
HCAR3 hydroxycarboxylic acid receptor 3
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
KDM3A lysine (K)-specific demethylase 3A
LCN2 lipocalin 2
LTF lactotransferrin
MME membrane metallo-endopeptidase
MMP7 matrix metallopeptidase 7
MNAT1 MNAT CDK-activating kinase assembly factor 1
MSMB microseminoprotein, beta-
MYBPC1 myosin binding protein C, slow type
PIR pirin (iron-binding nuclear protein)
PSAT1 phosphoserine aminotransferase 1
PYCARD PYD and CARD domain containing
S100A12 S100 calcium binding protein A12
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
ADORA2B adenosine A2b receptor
AREG amphiregulin
CAV2 caveolin 2
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CRABP1 cellular retinoic acid binding protein 1
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTSZ cathepsin Z
EGR1 early growth response 1
FAM57A family with sequence similarity 57, member A
FOSL1 FOS-like antigen 1
GAL galanin/GMAP prepropeptide
GPX3 glutathione peroxidase 3
GSTM3 glutathione S-transferase mu 3 (brain)
HOXB7 homeobox B7
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
MCM4 minichromosome maintenance complex component 4
NID1 nidogen 1
NPTX2 neuronal pentraxin II
PCOLCE procollagen C-endopeptidase enhancer
PHLDA2 pleckstrin homology-like domain, family A, member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPON1 spondin 1, extracellular matrix protein
SPTBN1 spectrin, beta, non-erythrocytic 1
TBX2 T-box 2
TUBB2A tubulin, beta 2A class IIa
VCAN versican