BRD-K08799216_pelitinib_BT20_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K08799216_pelitinib_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFD complement factor D (adipsin)
COL11A1 collagen, type XI, alpha 1
DACT1 dishevelled-binding antagonist of beta-catenin 1
FBLN1 fibulin 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
MAGEA3 melanoma antigen family A3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PCBP2 poly(rC) binding protein 2
PIR pirin (iron-binding nuclear protein)
PSD3 pleckstrin and Sec7 domain containing 3
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB31 RAB31, member RAS oncogene family
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
TSC22D3 TSC22 domain family, member 3
VCAN versican

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV2 caveolin 2
CPA3 carboxypeptidase A3 (mast cell)
CXCL14 chemokine (C-X-C motif) ligand 14
DLC1 DLC1 Rho GTPase activating protein
FAM134B family with sequence similarity 134, member B
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FOSL1 FOS-like antigen 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
IER3 immediate early response 3
LPL lipoprotein lipase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP7 matrix metallopeptidase 7
MRPS2 mitochondrial ribosomal protein S2
PAEP progestagen-associated endometrial protein
PEA15 phosphoprotein enriched in astrocytes 15
PNMA2 paraneoplastic Ma antigen 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC43A3 solute carrier family 43, member 3