BRD-K08777248_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K08777248_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ASPN asporin
AUTS2 autism susceptibility candidate 2
CD163 CD163 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COLEC12 collectin sub-family member 12
CPA3 carboxypeptidase A3 (mast cell)
FCGBP Fc fragment of IgG binding protein
FHL1 four and a half LIM domains 1
GAL galanin/GMAP prepropeptide
HIST1H2BG histone cluster 1, H2bg
METRN meteorin, glial cell differentiation regulator
MT1X metallothionein 1X
NPTX2 neuronal pentraxin II
PDE8B phosphodiesterase 8B
PLIN2 perilipin 2
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TCF4 transcription factor 4
VSIG4 V-set and immunoglobulin domain containing 4
XIST X inactive specific transcript (non-protein coding)
ZEB1 zinc finger E-box binding homeobox 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARMT1 acidic residue methyltransferase 1
BASP1 brain abundant, membrane attached signal protein 1
CALCA calcitonin-related polypeptide alpha
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHPT1 choline phosphotransferase 1
DYNLT3 dynein, light chain, Tctex-type 3
EGR3 early growth response 3
GSTP1 glutathione S-transferase pi 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HPRT1 hypoxanthine phosphoribosyltransferase 1
LDLR low density lipoprotein receptor
LYPLA1 lysophospholipase I
MARCKS myristoylated alanine-rich protein kinase C substrate
MFSD10 major facilitator superfamily domain containing 10
MOAP1 modulator of apoptosis 1
NEFH neurofilament, heavy polypeptide
NR4A2 nuclear receptor subfamily 4, group A, member 2
PBK PDZ binding kinase
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PEG10 paternally expressed 10
POU4F1 POU class 4 homeobox 1
PRPF4 pre-mRNA processing factor 4
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
SC5D sterol-C5-desaturase
SERINC5 serine incorporator 5
SGMS1 sphingomyelin synthase 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SMS spermine synthase
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SQLE squalene epoxidase
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TOP2A topoisomerase (DNA) II alpha 170kDa
TSPYL5 TSPY-like 5
XBP1 X-box binding protein 1
XPO7 exportin 7