BRD-K08619838_Tremorine dihydrochloride_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K08619838_Tremorine dihydrochloride_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
AGR2 anterior gradient 2
ALDOB aldolase B, fructose-bisphosphate
ANO1 anoctamin 1, calcium activated chloride channel
BMI1 BMI1 proto-oncogene, polycomb ring finger
CFI complement factor I
DDAH1 dimethylarginine dimethylaminohydrolase 1
ECI2 enoyl-CoA delta isomerase 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FMO1 flavin containing monooxygenase 1
G0S2 G0/G1 switch 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GNAS GNAS complex locus
GSTM3 glutathione S-transferase mu 3 (brain)
HDDC2 HD domain containing 2
HOXC6 homeobox C6
HP haptoglobin
HSDL2 hydroxysteroid dehydrogenase like 2
IL1R2 interleukin 1 receptor, type II
IL6ST interleukin 6 signal transducer
LASP1 LIM and SH3 protein 1
LRRC17 leucine rich repeat containing 17
LTF lactotransferrin
MAN1C1 mannosidase, alpha, class 1C, member 1
MARCKSL1 MARCKS-like 1
MDK midkine (neurite growth-promoting factor 2)
MGAM maltase-glucoamylase
NPR3 natriuretic peptide receptor 3
NRIP1 nuclear receptor interacting protein 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDZK1 PDZ domain containing 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLA2G16 phospholipase A2, group XVI
PLAT plasminogen activator, tissue
PODXL podocalyxin-like
PROM1 prominin 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSPH phosphoserine phosphatase
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RCAN1 regulator of calcineurin 1
RPA3 replication protein A3, 14kDa
S100A7 S100 calcium binding protein A7
SELL selectin L
SKP1 S-phase kinase-associated protein 1
STAT5B signal transducer and activator of transcription 5B
TBP TATA box binding protein
TFF1 trefoil factor 1
UBE2A ubiquitin-conjugating enzyme E2A
VCAN versican
YME1L1 YME1-like 1 ATPase

decreased expression

Symbol Name
ADCY2 adenylate cyclase 2 (brain)
ATM ATM serine/threonine kinase
CADM1 cell adhesion molecule 1
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COG7 component of oligomeric golgi complex 7
CSTA cystatin A (stefin A)
CTNND1 catenin (cadherin-associated protein), delta 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EIF4A1 eukaryotic translation initiation factor 4A1
EIF5B eukaryotic translation initiation factor 5B
FGFR2 fibroblast growth factor receptor 2
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GPNMB glycoprotein (transmembrane) nmb
GUSBP3 glucuronidase, beta pseudogene 3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGL immunoglobulin lambda locus
IPO13 importin 13
JAG1 jagged 1
LUM lumican
NDNF neuron-derived neurotrophic factor
NEFH neurofilament, heavy polypeptide
NPIPB3 nuclear pore complex interacting protein family, member B3
PAWR PRKC, apoptosis, WT1, regulator
PCSK1 proprotein convertase subtilisin/kexin type 1
PMP22 peripheral myelin protein 22
PRELP proline/arginine-rich end leucine-rich repeat protein
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFTPA2 surfactant protein A2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35E1 solute carrier family 35, member E1
SYT1 synaptotagmin I
TACC2 transforming, acidic coiled-coil containing protein 2
TES testin LIM domain protein
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM2 tripartite motif containing 2