BRD-K08619574_Thioproperazine dimesylate_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K08619574_Thioproperazine dimesylate_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
COL1A1 collagen, type I, alpha 1
CXCL8 chemokine (C-X-C motif) ligand 8
F13A1 coagulation factor XIII, A1 polypeptide
GPC3 glypican 3
GPX1 glutathione peroxidase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IL1RN interleukin 1 receptor antagonist
LAMP1 lysosomal-associated membrane protein 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PLEC plectin
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
RASA4 RAS p21 protein activator 4
TFF1 trefoil factor 1
TMEM259 transmembrane protein 259
TRAC T cell receptor alpha constant
TRD T cell receptor delta locus
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCND2 cyclin D2
CD38 CD38 molecule
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL13 chemokine (C-X-C motif) ligand 13
CYCS cytochrome c, somatic
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
GMNN geminin, DNA replication inhibitor
GULP1 GULP, engulfment adaptor PTB domain containing 1
NAMPT nicotinamide phosphoribosyltransferase
NPTX2 neuronal pentraxin II
NRIP1 nuclear receptor interacting protein 1
OBSL1 obscurin-like 1
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
REEP5 receptor accessory protein 5
TSPAN13 tetraspanin 13
UGCG UDP-glucose ceramide glucosyltransferase
VEGFA vascular endothelial growth factor A