BRD-K08502430_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

96 genes differentially expressed following the BRD-K08502430_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
AEBP1 AE binding protein 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
CBS cystathionine-beta-synthase
CCL19 chemokine (C-C motif) ligand 19
CD163 CD163 molecule
CFH complement factor H
CLEC7A C-type lectin domain family 7, member A
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL16A1 collagen, type XVI, alpha 1
CRABP1 cellular retinoic acid binding protein 1
CXCL9 chemokine (C-X-C motif) ligand 9
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
GARS glycyl-tRNA synthetase
GREM1 gremlin 1, DAN family BMP antagonist
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IFITM1 interferon induced transmembrane protein 1
KIF1A kinesin family member 1A
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NARS asparaginyl-tRNA synthetase
NUPR1 nuclear protein, transcriptional regulator, 1
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
RGS13 regulator of G-protein signaling 13
RGS16 regulator of G-protein signaling 16
TNNT1 troponin T type 1 (skeletal, slow)
XBP1 X-box binding protein 1
ZG16 zymogen granule protein 16
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
AIM1 absent in melanoma 1
AKAP7 A kinase (PRKA) anchor protein 7
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX5 arachidonate 5-lipoxygenase
ANKRD10 ankyrin repeat domain 10
AQP3 aquaporin 3 (Gill blood group)
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CALD1 caldesmon 1
CCNA2 cyclin A2
CCNB2 cyclin B2
CCNF cyclin F
CD69 CD69 molecule
CDC25B cell division cycle 25B
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CLCA2 chloride channel accessory 2
CXADR coxsackie virus and adenovirus receptor
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLD dihydrolipoamide dehydrogenase
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DPP4 dipeptidyl-peptidase 4
DST dystonin
FLNA filamin A, alpha
FZD7 frizzled class receptor 7
GJA1 gap junction protein, alpha 1, 43kDa
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPM6A glycoprotein M6A
HMMR hyaluronan-mediated motility receptor (RHAMM)
ITGA6 integrin, alpha 6
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
KIF2C kinesin family member 2C
KRT15 keratin 15, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LRRN3 leucine rich repeat neuronal 3
MMD monocyte to macrophage differentiation-associated
NQO1 NAD(P)H dehydrogenase, quinone 1
OPN3 opsin 3
PDE4B phosphodiesterase 4B, cAMP-specific
PGRMC1 progesterone receptor membrane component 1
PLK1 polo-like kinase 1
PPL periplakin
S100A7 S100 calcium binding protein A7
SPC25 SPC25, NDC80 kinetochore complex component
SYNM synemin, intermediate filament protein
TACSTD2 tumor-associated calcium signal transducer 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1