BRD-K08478539_RLM-2-12_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K08478539_RLM-2-12_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTC1 actin, alpha, cardiac muscle 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ANXA6 annexin A6
ARID5B AT rich interactive domain 5B (MRF1-like)
CNN1 calponin 1, basic, smooth muscle
EDN1 endothelin 1
EGF epidermal growth factor
EIF5A eukaryotic translation initiation factor 5A
FILIP1L filamin A interacting protein 1-like
GBP1 guanylate binding protein 1, interferon-inducible
GREB1 growth regulation by estrogen in breast cancer 1
MBNL1 muscleblind-like splicing regulator 1
MEIS2 Meis homeobox 2
MT1X metallothionein 1X
MYH11 myosin, heavy chain 11, smooth muscle
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDLIM3 PDZ and LIM domain 3
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLN phospholamban
SFRP1 secreted frizzled-related protein 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THBS1 thrombospondin 1
TPM2 tropomyosin 2 (beta)

decreased expression

Symbol Name
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FRZB frizzled-related protein
IGL immunoglobulin lambda locus
METTL7A methyltransferase like 7A
SEPP1 selenoprotein P, plasma, 1