BRD-K08463963_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K08463963_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
C3ORF14 chromosome 3 open reading frame 14
CADM1 cell adhesion molecule 1
CCL4 chemokine (C-C motif) ligand 4
COCH cochlin
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
EGR3 early growth response 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
HBB hemoglobin, beta
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IGFBP5 insulin-like growth factor binding protein 5
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
NR4A1 nuclear receptor subfamily 4, group A, member 1
PBX3 pre-B-cell leukemia homeobox 3
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
SCG5 secretogranin V
SGK1 serum/glucocorticoid regulated kinase 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SRSF7 serine/arginine-rich splicing factor 7
TARP TCR gamma alternate reading frame protein
TIMP3 TIMP metallopeptidase inhibitor 3
TPD52 tumor protein D52
ZC2HC1A zinc finger, C2HC-type containing 1A

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
BLVRB biliverdin reductase B
CDH3 cadherin 3, type 1, P-cadherin (placental)
CSTA cystatin A (stefin A)
FAM134B family with sequence similarity 134, member B
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NPY1R neuropeptide Y receptor Y1
NQO1 NAD(P)H dehydrogenase, quinone 1
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POU2AF1 POU class 2 associating factor 1
PSPH phosphoserine phosphatase
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCAND1 SCAN domain containing 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)