BRD-K08417745_SID 26681509_VCAP_24.0_h_88.8_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K08417745_SID 26681509_VCAP_24.0_h_88.8_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
APOA1 apolipoprotein A-I
APOD apolipoprotein D
CAV1 caveolin 1, caveolae protein, 22kDa
COLEC12 collectin sub-family member 12
DPYSL3 dihydropyrimidinase-like 3
EGFL6 EGF-like-domain, multiple 6
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
GAS1 growth arrest-specific 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGFBP3 insulin-like growth factor binding protein 3
INSIG1 insulin induced gene 1
KRT15 keratin 15, type I
KYNU kynureninase
LDLR low density lipoprotein receptor
MME membrane metallo-endopeptidase
MSMO1 methylsterol monooxygenase 1
PPAP2B phosphatidic acid phosphatase type 2B
PTGDS prostaglandin D2 synthase 21kDa (brain)
QPCT glutaminyl-peptide cyclotransferase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SQLE squalene epoxidase
SRPX sushi-repeat containing protein, X-linked
TGFBI transforming growth factor, beta-induced, 68kDa

decreased expression

Symbol Name
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BRCA1 breast cancer 1, early onset
CDC25A cell division cycle 25A
CDC45 cell division cycle 45
CDKN2A cyclin-dependent kinase inhibitor 2A
CHEK2 checkpoint kinase 2
GINS2 GINS complex subunit 2 (Psf2 homolog)
HAT1 histone acetyltransferase 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGKC immunoglobulin kappa constant
LAPTM4B lysosomal protein transmembrane 4 beta
LIG1 ligase I, DNA, ATP-dependent
MTA1 metastasis associated 1
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
PCCB propionyl CoA carboxylase, beta polypeptide
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RFC2 replication factor C (activator 1) 2, 40kDa
RPA3 replication protein A3, 14kDa
THBS1 thrombospondin 1
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
ZWINT ZW10 interacting kinetochore protein