BRD-K08417745_SID 26681509_HCC15_6.0_h_88.8_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K08417745_SID 26681509_HCC15_6.0_h_88.8_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALOX15B arachidonate 15-lipoxygenase, type B
ASNS asparagine synthetase (glutamine-hydrolyzing)
C6ORF62 chromosome 6 open reading frame 62
CBS cystathionine-beta-synthase
CD40 CD40 molecule, TNF receptor superfamily member 5
CPE carboxypeptidase E
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FXYD6 FXYD domain containing ion transport regulator 6
GCH1 GTP cyclohydrolase 1
H1F0 H1 histone family, member 0
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
JCHAIN joining chain of multimeric IgA and IgM
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MCL1 myeloid cell leukemia 1
MEIS1 Meis homeobox 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1M metallothionein 1M
MT1X metallothionein 1X
MTSS1 metastasis suppressor 1
NELL2 NEL-like 2 (chicken)
NIT1 nitrilase 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEA15 phosphoprotein enriched in astrocytes 15
PHGDH phosphoglycerate dehydrogenase
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RNASE4 ribonuclease, RNase A family, 4
RTN1 reticulon 1
RTN2 reticulon 2
SCN3A sodium channel, voltage gated, type III alpha subunit
SDC4 syndecan 4
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SOX9 SRY (sex determining region Y)-box 9
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
SYBU syntabulin (syntaxin-interacting)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TSC22D3 TSC22 domain family, member 3
ZNF232 zinc finger protein 232

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD2 abhydrolase domain containing 2
ACSL1 acyl-CoA synthetase long-chain family member 1
AK4 adenylate kinase 4
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATF5 activating transcription factor 5
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
COL5A1 collagen, type V, alpha 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DPYD dihydropyrimidine dehydrogenase
FBXO11 F-box protein 11
FGFR3 fibroblast growth factor receptor 3
FLNB filamin B, beta
GBE1 glucan (1,4-alpha-), branching enzyme 1
GOLGA8A golgin A8 family, member A
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IL1R2 interleukin 1 receptor, type II
KPNA4 karyopherin alpha 4 (importin alpha 3)
LDHB lactate dehydrogenase B
LTF lactotransferrin
MITF microphthalmia-associated transcription factor
MLANA melan-A
NID2 nidogen 2 (osteonidogen)
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PCYOX1 prenylcysteine oxidase 1
PDLIM1 PDZ and LIM domain 1
PI3 peptidase inhibitor 3, skin-derived
PLAT plasminogen activator, tissue
PLBD1 phospholipase B domain containing 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRAME preferentially expressed antigen in melanoma
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A12 S100 calcium binding protein A12
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SATB2 SATB homeobox 2
SLC35F2 solute carrier family 35, member F2
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR1A small proline-rich protein 1A
SPRR2B small proline-rich protein 2B
STEAP1 six transmembrane epithelial antigen of the prostate 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TYRP1 tyrosinase-related protein 1
WNT5A wingless-type MMTV integration site family, member 5A
ZBTB38 zinc finger and BTB domain containing 38