BRD-K08417745_SID 26681509_A375_6.0_h_88.8_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K08417745_SID 26681509_A375_6.0_h_88.8_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AARS alanyl-tRNA synthetase
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANKRD10 ankyrin repeat domain 10
ATF4 activating transcription factor 4
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
DDIT3 DNA-damage-inducible transcript 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
NUPR1 nuclear protein, transcriptional regulator, 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
SLC38A1 solute carrier family 38, member 1
TRIB3 tribbles pseudokinase 3
TXNRD1 thioredoxin reductase 1
VWF von Willebrand factor
WARS tryptophanyl-tRNA synthetase
XBP1 X-box binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
AURKA aurora kinase A
CCND1 cyclin D1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ERBB3 erb-b2 receptor tyrosine kinase 3
EREG epiregulin
QDPR quinoid dihydropteridine reductase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SOX2 SRY (sex determining region Y)-box 2
TMEM2 transmembrane protein 2