BRD-K08307026_-666_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K08307026_-666_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP1 dual specificity phosphatase 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM162A family with sequence similarity 162, member A
GADD45B growth arrest and DNA-damage-inducible, beta
H1F0 H1 histone family, member 0
HMOX1 heme oxygenase 1
KDM5D lysine (K)-specific demethylase 5D
MSX1 msh homeobox 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NDRG1 N-myc downstream regulated 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM2 PDZ and LIM domain 2 (mystique)
PHGDH phosphoglycerate dehydrogenase
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARD peroxisome proliferator-activated receptor delta
RCAN1 regulator of calcineurin 1
RIOK3 RIO kinase 3
RNMT RNA (guanine-7-) methyltransferase
RPS4Y1 ribosomal protein S4, Y-linked 1
S100P S100 calcium binding protein P
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TNIP1 TNFAIP3 interacting protein 1
TOB1 transducer of ERBB2, 1
TXNIP thioredoxin interacting protein
ZMYM2 zinc finger, MYM-type 2

decreased expression

Symbol Name
AURKB aurora kinase B
C3 complement component 3
C7 complement component 7
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CD24 CD24 molecule
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC2B C-type lectin domain family 2, member B
FHOD3 formin homology 2 domain containing 3
GREB1 growth regulation by estrogen in breast cancer 1
IGHM immunoglobulin heavy constant mu
IL13RA2 interleukin 13 receptor, alpha 2
KIAA0753 KIAA0753
KRT13 keratin 13, type I
KRT19 keratin 19, type I
LOC100505650 uncharacterized LOC100505650
LXN latexin
MYOF myoferlin
NEB nebulin
PCSK1 proprotein convertase subtilisin/kexin type 1
PEG3 paternally expressed 3
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFRP4 secreted frizzled-related protein 4
SMC1A structural maintenance of chromosomes 1A
SPON1 spondin 1, extracellular matrix protein
SPON2 spondin 2, extracellular matrix protein
SVIL supervillin