BRD-K08252256_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

22 genes differentially expressed following the BRD-K08252256_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANO1 anoctamin 1, calcium activated chloride channel
MCOLN1 mucolipin 1
MME membrane metallo-endopeptidase
PDZD2 PDZ domain containing 2
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
SCGB2A1 secretoglobin, family 2A, member 1
SPRED2 sprouty-related, EVH1 domain containing 2
TCF4 transcription factor 4
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
ZEB1 zinc finger E-box binding homeobox 1

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
EDF1 endothelial differentiation-related factor 1
FAM46A family with sequence similarity 46, member A
GALC galactosylceramidase
GPRC5A G protein-coupled receptor, class C, group 5, member A
MMP12 matrix metallopeptidase 12
RNF167 ring finger protein 167
STOM stomatin
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1
VCAN versican