BRD-K08219523_5-nonyloxytryptamine_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

154 genes differentially expressed following the BRD-K08219523_5-nonyloxytryptamine_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ALCAM activated leukocyte cell adhesion molecule
ARG2 arginase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CAPG capping protein (actin filament), gelsolin-like
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CD40 CD40 molecule, TNF receptor superfamily member 5
CD52 CD52 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFD complement factor D (adipsin)
CPA3 carboxypeptidase A3 (mast cell)
CTBP2 C-terminal binding protein 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP4 dual specificity phosphatase 4
EBP emopamil binding protein (sterol isomerase)
EPAS1 endothelial PAS domain protein 1
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
FGG fibrinogen gamma chain
FGR FGR proto-oncogene, Src family tyrosine kinase
FRY furry homolog (Drosophila)
FTH1 ferritin, heavy polypeptide 1
GARS glycyl-tRNA synthetase
GLS glutaminase
GPR137B G protein-coupled receptor 137B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMG20B high mobility group 20B
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INSIG1 insulin induced gene 1
IPO13 importin 13
KLF4 Kruppel-like factor 4 (gut)
LDLR low density lipoprotein receptor
LPIN1 lipin 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
MOCOS molybdenum cofactor sulfurase
MSMO1 methylsterol monooxygenase 1
MT1X metallothionein 1X
NEU1 sialidase 1 (lysosomal sialidase)
NFIL3 nuclear factor, interleukin 3 regulated
NPC1 Niemann-Pick disease, type C1
NPTX2 neuronal pentraxin II
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUPR1 nuclear protein, transcriptional regulator, 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE2A phosphodiesterase 2A, cGMP-stimulated
PHGDH phosphoglycerate dehydrogenase
PLIN2 perilipin 2
POLR1D polymerase (RNA) I polypeptide D, 16kDa
PPL periplakin
PSAP prosaposin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
RGCC regulator of cell cycle
RHOB ras homolog family member B
SARS seryl-tRNA synthetase
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPON2 spondin 2, extracellular matrix protein
SQLE squalene epoxidase
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
TRIB3 tribbles pseudokinase 3
TSC22D1 TSC22 domain family, member 1
TSC22D3 TSC22 domain family, member 3
VAT1 vesicle amine transport 1
VEGFA vascular endothelial growth factor A
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADGRA3 adhesion G protein-coupled receptor A3
AK1 adenylate kinase 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
CADM1 cell adhesion molecule 1
CCL2 chemokine (C-C motif) ligand 2
CD24 CD24 molecule
CDC5L cell division cycle 5-like
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CFI complement factor I
COL3A1 collagen, type III, alpha 1
CYR61 cysteine-rich, angiogenic inducer, 61
DAPK1 death-associated protein kinase 1
DHFR dihydrofolate reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FASTKD5 FAST kinase domains 5
FERMT1 fermitin family member 1
FKBP1A FK506 binding protein 1A, 12kDa
FYB FYN binding protein
GBP1 guanylate binding protein 1, interferon-inducible
GLIPR1 GLI pathogenesis-related 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSPB8 heat shock 22kDa protein 8
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IRF1 interferon regulatory factor 1
ISOC1 isochorismatase domain containing 1
KLF10 Kruppel-like factor 10
LYPD1 LY6/PLAUR domain containing 1
MAP2K3 mitogen-activated protein kinase kinase 3
MATN2 matrilin 2
PFN2 profilin 2
PI3 peptidase inhibitor 3, skin-derived
PLK1 polo-like kinase 1
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RBP1 retinol binding protein 1, cellular
RNASET2 ribonuclease T2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
STAT1 signal transducer and activator of transcription 1, 91kDa
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TMEM230 transmembrane protein 230
TPM1 tropomyosin 1 (alpha)
TSPAN7 tetraspanin 7
WWTR1 WW domain containing transcription regulator 1
ZWINT ZW10 interacting kinetochore protein