BRD-K08109215_I-BET_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K08109215_I-BET_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDOB aldolase B, fructose-bisphosphate
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
C3ORF14 chromosome 3 open reading frame 14
CDC42 cell division cycle 42
CELF2 CUGBP, Elav-like family member 2
CIRBP cold inducible RNA binding protein
CYBB cytochrome b-245, beta polypeptide
EIF5A eukaryotic translation initiation factor 5A
FGL2 fibrinogen-like 2
GCA grancalcin, EF-hand calcium binding protein
GRN granulin
HIPK1 homeodomain interacting protein kinase 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IQGAP1 IQ motif containing GTPase activating protein 1
JUND jun D proto-oncogene
LAPTM4B lysosomal protein transmembrane 4 beta
LITAF lipopolysaccharide-induced TNF factor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NBPF10 neuroblastoma breakpoint family, member 10
NR4A2 nuclear receptor subfamily 4, group A, member 2
PALLD palladin, cytoskeletal associated protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PTN pleiotrophin
RPL37A ribosomal protein L37a
RRAGD Ras-related GTP binding D
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
TPD52L1 tumor protein D52-like 1
TTC3 tetratricopeptide repeat domain 3
TUBB2A tubulin, beta 2A class IIa
VNN1 vanin 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
AQP1 aquaporin 1 (Colton blood group)
C3 complement component 3
CFB complement factor B
CHI3L2 chitinase 3-like 2
EGFL6 EGF-like-domain, multiple 6
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GNAS GNAS complex locus
GOLGA8A golgin A8 family, member A
GRIA2 glutamate receptor, ionotropic, AMPA 2
GTF3A general transcription factor IIIA
HACD1 3-hydroxyacyl-CoA dehydratase 1
HBB hemoglobin, beta
IGFBP3 insulin-like growth factor binding protein 3
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LOX lysyl oxidase
LTF lactotransferrin
LUM lumican
LYZ lysozyme
MAL mal, T-cell differentiation protein
MPZL2 myelin protein zero-like 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
ODAM odontogenic, ameloblast asssociated
PDGFC platelet derived growth factor C
PI3 peptidase inhibitor 3, skin-derived
POSTN periostin, osteoblast specific factor
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
S100A4 S100 calcium binding protein A4
SFTPB surfactant protein B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6