BRD-K08109215_I-BET_HT29_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K08109215_I-BET_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
BMP2 bone morphogenetic protein 2
CADM1 cell adhesion molecule 1
CD36 CD36 molecule (thrombospondin receptor)
CD59 CD59 molecule, complement regulatory protein
ETV1 ets variant 1
EXOSC4 exosome component 4
FABP7 fatty acid binding protein 7, brain
FAM3C family with sequence similarity 3, member C
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPC3 glypican 3
GPNMB glycoprotein (transmembrane) nmb
ITGA6 integrin, alpha 6
KRT19 keratin 19, type I
NPIPB3 nuclear pore complex interacting protein family, member B3
PKM pyruvate kinase, muscle
RHOBTB3 Rho-related BTB domain containing 3
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPP1 selenoprotein P, plasma, 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SPTSSA serine palmitoyltransferase, small subunit A
SQSTM1 sequestosome 1
TCF4 transcription factor 4
TPD52L1 tumor protein D52-like 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AREG amphiregulin
C3 complement component 3
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
COL5A1 collagen, type V, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EREG epiregulin
EVI2B ecotropic viral integration site 2B
FAM129A family with sequence similarity 129, member A
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
IFITM1 interferon induced transmembrane protein 1
JADE2 jade family PHD finger 2
KRT23 keratin 23, type I
MAPT microtubule-associated protein tau
MTA1 metastasis associated 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PXMP2 peroxisomal membrane protein 2, 22kDa
RGS10 regulator of G-protein signaling 10
SOCS2 suppressor of cytokine signaling 2
SOX11 SRY (sex determining region Y)-box 11
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULF1 sulfatase 1
SYT1 synaptotagmin I
THBS1 thrombospondin 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIMP1 TIMP metallopeptidase inhibitor 1
TMC5 transmembrane channel-like 5
TNS1 tensin 1
TUBB2A tubulin, beta 2A class IIa
VCAN versican
XIST X inactive specific transcript (non-protein coding)