BRD-K08109215_I-BET_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K08109215_I-BET_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C14ORF132 chromosome 14 open reading frame 132
CADM1 cell adhesion molecule 1
CLDN10 claudin 10
CP ceruloplasmin (ferroxidase)
DAPK1 death-associated protein kinase 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
OXA1L oxidase (cytochrome c) assembly 1-like
PCDH9 protocadherin 9
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RPL39L ribosomal protein L39-like
SCGB2A1 secretoglobin, family 2A, member 1
VDAC1 voltage-dependent anion channel 1
VTCN1 V-set domain containing T cell activation inhibitor 1
WFS1 Wolfram syndrome 1 (wolframin)
WT1 Wilms tumor 1

decreased expression

Symbol Name
ACAA1 acetyl-CoA acyltransferase 1
AIM1 absent in melanoma 1
ANPEP alanyl (membrane) aminopeptidase
ANXA3 annexin A3
AQP1 aquaporin 1 (Colton blood group)
AXL AXL receptor tyrosine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BPHL biphenyl hydrolase-like (serine hydrolase)
CA2 carbonic anhydrase II
CCL2 chemokine (C-C motif) ligand 2
CFD complement factor D (adipsin)
COPS7A COP9 signalosome subunit 7A
COTL1 coactosin-like F-actin binding protein 1
CXCL14 chemokine (C-X-C motif) ligand 14
DKK1 dickkopf WNT signaling pathway inhibitor 1
DRAM1 DNA-damage regulated autophagy modulator 1
DST dystonin
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EMP3 epithelial membrane protein 3
FABP7 fatty acid binding protein 7, brain
FAM129A family with sequence similarity 129, member A
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FOSL1 FOS-like antigen 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP1 guanylate binding protein 1, interferon-inducible
GSTA1 glutathione S-transferase alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOPX HOP homeobox
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL32 interleukin 32
ISG15 ISG15 ubiquitin-like modifier
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LOX lysyl oxidase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1M metallothionein 1M
MYBPC1 myosin binding protein C, slow type
PCOLCE2 procollagen C-endopeptidase enhancer 2
POSTN periostin, osteoblast specific factor
PTPRC protein tyrosine phosphatase, receptor type, C
S100A2 S100 calcium binding protein A2
SFRP1 secreted frizzled-related protein 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
XPO7 exportin 7