BRD-K07888196_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K07888196_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
AGR2 anterior gradient 2
AQP1 aquaporin 1 (Colton blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
C8ORF4 chromosome 8 open reading frame 4
CLIC4 chloride intracellular channel 4
CTGF connective tissue growth factor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
ELF5 E74-like factor 5 (ets domain transcription factor)
FAM46A family with sequence similarity 46, member A
FBP1 fructose-1,6-bisphosphatase 1
GPM6B glycoprotein M6B
H1F0 H1 histone family, member 0
LTF lactotransferrin
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
MFAP5 microfibrillar associated protein 5
MFSD10 major facilitator superfamily domain containing 10
MTUS1 microtubule associated tumor suppressor 1
NTS neurotensin
PLAU plasminogen activator, urokinase
SATB1 SATB homeobox 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SNX11 sorting nexin 11
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
CASP6 caspase 6, apoptosis-related cysteine peptidase
CAST calpastatin
CD36 CD36 molecule (thrombospondin receptor)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CES1 carboxylesterase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
DKK3 dickkopf WNT signaling pathway inhibitor 3
EMP2 epithelial membrane protein 2
ERAP2 endoplasmic reticulum aminopeptidase 2
EREG epiregulin
FHL1 four and a half LIM domains 1
IFT57 intraflagellar transport 57
IGFBP5 insulin-like growth factor binding protein 5
KANK1 KN motif and ankyrin repeat domains 1
KRT23 keratin 23, type I
LOC100505650 uncharacterized LOC100505650
LPL lipoprotein lipase
MDK midkine (neurite growth-promoting factor 2)
NEB nebulin
PDGFC platelet derived growth factor C
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A6 S100 calcium binding protein A6
S100A8 S100 calcium binding protein A8
SCARB2 scavenger receptor class B, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SRGN serglycin
STK10 serine/threonine kinase 10
SYT1 synaptotagmin I
THY1 Thy-1 cell surface antigen
TLR4 toll-like receptor 4
TPBG trophoblast glycoprotein
TPD52L1 tumor protein D52-like 1
XIST X inactive specific transcript (non-protein coding)