BRD-K07303502_Arachidonyl trifluoro-methyl ketone_JHUEM2_6.0_h_80.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

126 genes differentially expressed following the BRD-K07303502_Arachidonyl trifluoro-methyl ketone_JHUEM2_6.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
AMIGO2 adhesion molecule with Ig-like domain 2
AQP3 aquaporin 3 (Gill blood group)
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
BAG3 BCL2-associated athanogene 3
BBX bobby sox homolog (Drosophila)
BTG1 B-cell translocation gene 1, anti-proliferative
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C6ORF48 chromosome 6 open reading frame 48
CA12 carbonic anhydrase XII
CD163 CD163 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLEC3B C-type lectin domain family 3, member B
CLIC4 chloride intracellular channel 4
CPE carboxypeptidase E
CSRP1 cysteine and glycine-rich protein 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
EDNRA endothelin receptor type A
EFNA1 ephrin-A1
EIF5A eukaryotic translation initiation factor 5A
EPAS1 endothelial PAS domain protein 1
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
FABP7 fatty acid binding protein 7, brain
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXO4 forkhead box O4
GLRX glutaredoxin (thioltransferase)
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
H2BFS H2B histone family, member S (pseudogene)
HECA headcase homolog (Drosophila)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOXA10 homeobox A10
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFRD1 interferon-related developmental regulator 1
JUN jun proto-oncogene
JUND jun D proto-oncogene
KIAA1598
KLF4 Kruppel-like factor 4 (gut)
KRT19 keratin 19, type I
LXN latexin
MAP7 microtubule-associated protein 7
MAPK13 mitogen-activated protein kinase 13
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEIS1 Meis homeobox 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MSX1 msh homeobox 1
MT2A metallothionein 2A
MTUS1 microtubule associated tumor suppressor 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYH11 myosin, heavy chain 11, smooth muscle
NEFM neurofilament, medium polypeptide
NFIL3 nuclear factor, interleukin 3 regulated
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRIP1 nuclear receptor interacting protein 1
PEG3 paternally expressed 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKP1 plakophilin 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTHLH parathyroid hormone-like hormone
PTN pleiotrophin
PTP4A1 protein tyrosine phosphatase type IVA, member 1
REEP1 receptor accessory protein 1
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SFN stratifin
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SOBP sine oculis binding protein homolog (Drosophila)
STC2 stanniocalcin 2
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TBPL1 TBP-like 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNC tenascin C
TSC22D3 TSC22 domain family, member 3
TSPAN13 tetraspanin 13
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
TXNL4B thioredoxin-like 4B
VSIG4 V-set and immunoglobulin domain containing 4
ZFP36 ZFP36 ring finger protein
ZNF292 zinc finger protein 292
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CA2 carbonic anhydrase II
CCNA2 cyclin A2
CCNE2 cyclin E2
CCNF cyclin F
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL5A2 collagen, type V, alpha 2
DEFB1 defensin, beta 1
GAS1 growth arrest-specific 1
GPX1 glutathione peroxidase 1
GSPT2 G1 to S phase transition 2
IRX5 iroquois homeobox 5
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KANK1 KN motif and ankyrin repeat domains 1
KDM4B lysine (K)-specific demethylase 4B
LOX lysyl oxidase
MXRA5 matrix-remodelling associated 5
MYB v-myb avian myeloblastosis viral oncogene homolog
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SRSF1 serine/arginine-rich splicing factor 1
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
UBQLN2 ubiquilin 2