BRD-K07303502_Arachidonyl trifluoro-methyl ketone_HCC515_6.0_h_80.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

118 genes differentially expressed following the BRD-K07303502_Arachidonyl trifluoro-methyl ketone_HCC515_6.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
CACYBP calcyclin binding protein
CBR3 carbonyl reductase 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLU clusterin
CTH cystathionine gamma-lyase
DDIT3 DNA-damage-inducible transcript 3
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EGR1 early growth response 1
EGR3 early growth response 3
FOSL1 FOS-like antigen 1
FXR1 fragile X mental retardation, autosomal homolog 1
GCLM glutamate-cysteine ligase, modifier subunit
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IFRD1 interferon-related developmental regulator 1
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KDM5D lysine (K)-specific demethylase 5D
KIAA0226L KIAA0226-like
KRT19 keratin 19, type I
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MGAM maltase-glucoamylase
NEFL neurofilament, light polypeptide
NQO1 NAD(P)H dehydrogenase, quinone 1
OSER1 oxidative stress responsive serine-rich 1
PIR pirin (iron-binding nuclear protein)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STC2 stanniocalcin 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TBPL1 TBP-like 1
TKT transketolase
TPD52L1 tumor protein D52-like 1
TSPAN13 tetraspanin 13
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL4C ADP-ribosylation factor-like 4C
ATF5 activating transcription factor 5
BAMBI BMP and activin membrane-bound inhibitor
BHLHE40 basic helix-loop-helix family, member e40
CCL2 chemokine (C-C motif) ligand 2
CCNB1 cyclin B1
CCND2 cyclin D2
CCNF cyclin F
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHGB chromogranin B
COL4A5 collagen, type IV, alpha 5
CP ceruloplasmin (ferroxidase)
DERA deoxyribose-phosphate aldolase (putative)
FGFR3 fibroblast growth factor receptor 3
FLRT2 fibronectin leucine rich transmembrane protein 2
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GAS1 growth arrest-specific 1
GREM1 gremlin 1, DAN family BMP antagonist
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
IGFBP3 insulin-like growth factor binding protein 3
KCTD12 potassium channel tetramerization domain containing 12
LGALS1 lectin, galactoside-binding, soluble, 1
MCOLN1 mucolipin 1
MEIS1 Meis homeobox 1
MYRF myelin regulatory factor
NFIB nuclear factor I/B
NNMT nicotinamide N-methyltransferase
PBX1 pre-B-cell leukemia homeobox 1
PDLIM3 PDZ and LIM domain 3
PRSS21 protease, serine, 21 (testisin)
PTGIS prostaglandin I2 (prostacyclin) synthase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS2 regulator of G-protein signaling 2
RIN2 Ras and Rab interactor 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SOX4 SRY (sex determining region Y)-box 4
SPON1 spondin 1, extracellular matrix protein
SPRY2 sprouty homolog 2 (Drosophila)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
TFRC transferrin receptor
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TRD T cell receptor delta locus
TRIL TLR4 interactor with leucine-rich repeats
TSPAN12 tetraspanin 12
TSPAN8 tetraspanin 8