BRD-K07079548_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K07079548_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK AHNAK nucleoprotein
CAPN2 calpain 2, (m/II) large subunit
CCL5 chemokine (C-C motif) ligand 5
CD81 CD81 molecule
FAM129A family with sequence similarity 129, member A
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GOLM1 golgi membrane protein 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ILK integrin-linked kinase
LDHB lactate dehydrogenase B
LDLR low density lipoprotein receptor
MAGEA6 melanoma antigen family A6
MSLN mesothelin
MSMO1 methylsterol monooxygenase 1
NT5E 5'-nucleotidase, ecto (CD73)
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRSS23 protease, serine, 23
S100A10 S100 calcium binding protein A10
TRAPPC3 trafficking protein particle complex 3
TSPAN4 tetraspanin 4

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ARMCX2 armadillo repeat containing, X-linked 2
BHLHE41 basic helix-loop-helix family, member e41
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL3A1 collagen, type III, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
DCN decorin
DHRS2 dehydrogenase/reductase (SDR family) member 2
EDNRB endothelin receptor type B
ELN elastin
HES1 hes family bHLH transcription factor 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HTRA1 HtrA serine peptidase 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL1R1 interleukin 1 receptor, type I
LPL lipoprotein lipase
LUM lumican
MFAP2 microfibrillar-associated protein 2
MYH10 myosin, heavy chain 10, non-muscle
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBP4 retinol binding protein 4, plasma
RGS2 regulator of G-protein signaling 2
SEPP1 selenoprotein P, plasma, 1
SNX7 sorting nexin 7
SPON1 spondin 1, extracellular matrix protein
TGFB3 transforming growth factor, beta 3
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17