BRD-K07023879_-666_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K07023879_-666_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA3 annexin A3
BST2 bone marrow stromal cell antigen 2
CD24 CD24 molecule
CDC42 cell division cycle 42
CRYAB crystallin, alpha B
CTSH cathepsin H
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GUSBP3 glucuronidase, beta pseudogene 3
HNMT histamine N-methyltransferase
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
KIAA0101 KIAA0101
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
OXA1L oxidase (cytochrome c) assembly 1-like
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAC8 placenta-specific 8
REXO2 RNA exonuclease 2
RPS11 ribosomal protein S11
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
VCAN versican
VDAC1 voltage-dependent anion channel 1
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
CAV1 caveolin 1, caveolae protein, 22kDa
CD44 CD44 molecule (Indian blood group)
CHN1 chimerin 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL15A1 collagen, type XV, alpha 1
DLK1 delta-like 1 homolog (Drosophila)
FST follistatin
HHEX hematopoietically expressed homeobox
IGFBP5 insulin-like growth factor binding protein 5
IL13RA1 interleukin 13 receptor, alpha 1
IL6ST interleukin 6 signal transducer
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SOCS2 suppressor of cytokine signaling 2