BRD-K07005393_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-K07005393_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
FASN fatty acid synthase
FOS FBJ murine osteosarcoma viral oncogene homolog
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
HES1 hes family bHLH transcription factor 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
JUND jun D proto-oncogene
NSDHL NAD(P) dependent steroid dehydrogenase-like
PKM pyruvate kinase, muscle
SCNN1A sodium channel, non voltage gated 1 alpha subunit

decreased expression

Symbol Name
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GYPC glycophorin C (Gerbich blood group)
HRSP12 heat-responsive protein 12
IFITM1 interferon induced transmembrane protein 1
IL13RA2 interleukin 13 receptor, alpha 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PLCB4 phospholipase C, beta 4
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
TMEM45A transmembrane protein 45A