BRD-K06980535_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K06980535_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
ACSL3 acyl-CoA synthetase long-chain family member 3
AHNAK2 AHNAK nucleoprotein 2
ANXA3 annexin A3
ARG2 arginase 2
CAB39 calcium binding protein 39
CBS cystathionine-beta-synthase
CCNA1 cyclin A1
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPE carboxypeptidase E
CST6 cystatin E/M
CTSG cathepsin G
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DHCR7 7-dehydrocholesterol reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMXL2 Dmx-like 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FDPS farnesyl diphosphate synthase
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GAL galanin/GMAP prepropeptide
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GREM1 gremlin 1, DAN family BMP antagonist
HBEGF heparin-binding EGF-like growth factor
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDI1 isopentenyl-diphosphate delta isomerase 1
KCTD12 potassium channel tetramerization domain containing 12
LDLR low density lipoprotein receptor
LGALS4 lectin, galactoside-binding, soluble, 4
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MME membrane metallo-endopeptidase
MSMO1 methylsterol monooxygenase 1
OLFM4 olfactomedin 4
PEG3 paternally expressed 3
PTX3 pentraxin 3, long
QPCT glutaminyl-peptide cyclotransferase
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFN stratifin
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SOX9 SRY (sex determining region Y)-box 9
SQLE squalene epoxidase
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
VEGFA vascular endothelial growth factor A
VIM vimentin

decreased expression

Symbol Name
CADM1 cell adhesion molecule 1
DMD dystrophin
EVL Enah/Vasp-like
GADD45B growth arrest and DNA-damage-inducible, beta
HEBP1 heme binding protein 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXC6 homeobox C6
MTUS1 microtubule associated tumor suppressor 1
PLAGL1 pleiomorphic adenoma gene-like 1
PRR15L proline rich 15-like