BRD-K06956503_NCGC00187945-01_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K06956503_NCGC00187945-01_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDOC aldolase C, fructose-bisphosphate
ASNS asparagine synthetase (glutamine-hydrolyzing)
CD24 CD24 molecule
CD9 CD9 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL11A1 collagen, type XI, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FABP4 fatty acid binding protein 4, adipocyte
GATA3 GATA binding protein 3
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IGHD immunoglobulin heavy constant delta
INSIG1 insulin induced gene 1
KRT15 keratin 15, type I
KRT19 keratin 19, type I
LDLR low density lipoprotein receptor
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP13 matrix metallopeptidase 13
MSMO1 methylsterol monooxygenase 1
MTCL1 microtubule crosslinking factor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NSDHL NAD(P) dependent steroid dehydrogenase-like
PEG10 paternally expressed 10
POU4F1 POU class 4 homeobox 1
PSPH phosphoserine phosphatase
PVALB parvalbumin
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SGCE sarcoglycan, epsilon
SQLE squalene epoxidase
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TP63 tumor protein p63

decreased expression

Symbol Name
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
BST2 bone marrow stromal cell antigen 2
CA2 carbonic anhydrase II
CEP70 centrosomal protein 70kDa
COL18A1 collagen, type XVIII, alpha 1
COL6A2 collagen, type VI, alpha 2
CRIP2 cysteine-rich protein 2
GPX3 glutathione peroxidase 3
GRB14 growth factor receptor-bound protein 14
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
MLPH melanophilin
PBX3 pre-B-cell leukemia homeobox 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PODXL podocalyxin-like
PRKACB protein kinase, cAMP-dependent, catalytic, beta
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SNX10 sorting nexin 10
TGM2 transglutaminase 2
TMSB15A thymosin beta 15a