BRD-K06765193_(E)-2-(1H-Benzoimidazol-2-yl)-3-(5-nitro-furan-2-yl)-acrylonitrile BRD-K06765193_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K06765193_(E)-2-(1H-Benzoimidazol-2-yl)-3-(5-nitro-furan-2-yl)-acrylonitrile BRD-K06765193_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
GPM6B glycoprotein M6B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HP haptoglobin
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
MPO myeloperoxidase
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SRGN serglycin

decreased expression

Symbol Name
ARHGAP29 Rho GTPase activating protein 29
CCL19 chemokine (C-C motif) ligand 19
CCNB2 cyclin B2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL9 chemokine (C-X-C motif) ligand 9
DUOX2 dual oxidase 2
IL1B interleukin 1, beta
NFIB nuclear factor I/B
NRIP1 nuclear receptor interacting protein 1
PEG10 paternally expressed 10
TACC2 transforming, acidic coiled-coil containing protein 2
TFRC transferrin receptor
TM4SF1 transmembrane 4 L six family member 1