BRD-K06623064_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

91 genes differentially expressed following the BRD-K06623064_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANGPT2 angiopoietin 2
ATP11B ATPase, class VI, type 11B
AUTS2 autism susceptibility candidate 2
CA2 carbonic anhydrase II
CCNE2 cyclin E2
CD14 CD14 molecule
CD163 CD163 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC5A C-type lectin domain family 5, member A
COL15A1 collagen, type XV, alpha 1
CPE carboxypeptidase E
CRISP3 cysteine-rich secretory protein 3
CX3CR1 chemokine (C-X3-C motif) receptor 1
DLK1 delta-like 1 homolog (Drosophila)
FCGBP Fc fragment of IgG binding protein
FGFR3 fibroblast growth factor receptor 3
GLUL glutamate-ammonia ligase
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
INSM1 insulinoma-associated 1
ISOC1 isochorismatase domain containing 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLK10 kallikrein-related peptidase 10
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7 microtubule-associated protein 7
METTL7A methyltransferase like 7A
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP9 matrix metallopeptidase 9
MPZL2 myelin protein zero-like 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PEG3 paternally expressed 3
PERP PERP, TP53 apoptosis effector
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLVAP plasmalemma vesicle associated protein
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS5 regulator of G-protein signaling 5
SCGB2A2 secretoglobin, family 2A, member 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SPARCL1 SPARC-like 1 (hevin)
THBD thrombomodulin
VSIG4 V-set and immunoglobulin domain containing 4
VWF von Willebrand factor
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA5 annexin A5
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BST2 bone marrow stromal cell antigen 2
C9ORF3 chromosome 9 open reading frame 3
CCL20 chemokine (C-C motif) ligand 20
CCND1 cyclin D1
CD151 CD151 molecule (Raph blood group)
CDC42 cell division cycle 42
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FOLR1 folate receptor 1 (adult)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
GADD45B growth arrest and DNA-damage-inducible, beta
HOXB7 homeobox B7
IFI6 interferon, alpha-inducible protein 6
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KDM5D lysine (K)-specific demethylase 5D
L1CAM L1 cell adhesion molecule
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
NME4 NME/NM23 nucleoside diphosphate kinase 4
NPY1R neuropeptide Y receptor Y1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDIA5 protein disulfide isomerase family A, member 5
PFKP phosphofructokinase, platelet
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAC8 placenta-specific 8
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMAD7 SMAD family member 7
TGM2 transglutaminase 2
TMED3 transmembrane emp24 protein transport domain containing 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNIP1 TNFAIP3 interacting protein 1
UGCG UDP-glucose ceramide glucosyltransferase
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2
ZBTB18 zinc finger and BTB domain containing 18