BRD-K06593056_-666_MCF7_6.0_h_20.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K06593056_-666_MCF7_6.0_h_20.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANKRD10 ankyrin repeat domain 10
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
IGFBP7 insulin-like growth factor binding protein 7
MT1F metallothionein 1F
MT1M metallothionein 1M
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPS4Y1 ribosomal protein S4, Y-linked 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TMEM176B transmembrane protein 176B
TNNT1 troponin T type 1 (skeletal, slow)
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
WASF1 WAS protein family, member 1
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IQGAP1 IQ motif containing GTPase activating protein 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
RPS11 ribosomal protein S11
S100A9 S100 calcium binding protein A9
TARP TCR gamma alternate reading frame protein
TFRC transferrin receptor
TMEM164 transmembrane protein 164
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)