BRD-K06593056_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K06593056_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BCL6 B-cell CLL/lymphoma 6
BTG2 BTG family, member 2
C5AR1 complement component 5a receptor 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOS FBJ murine osteosarcoma viral oncogene homolog
G0S2 G0/G1 switch 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IFRD1 interferon-related developmental regulator 1
IL1R2 interleukin 1 receptor, type II
MT2A metallothionein 2A
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SLC38A1 solute carrier family 38, member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
UPP1 uridine phosphorylase 1

decreased expression

Symbol Name
GLO1 glyoxalase I
MAP3K5 mitogen-activated protein kinase kinase kinase 5
NPR3 natriuretic peptide receptor 3
PLK1 polo-like kinase 1
RNF167 ring finger protein 167
S100A7 S100 calcium binding protein A7
SRC SRC proto-oncogene, non-receptor tyrosine kinase
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon