BRD-K06593056_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K06593056_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BCL6 B-cell CLL/lymphoma 6
C6ORF48 chromosome 6 open reading frame 48
CARS cysteinyl-tRNA synthetase
CBS cystathionine-beta-synthase
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
ECM1 extracellular matrix protein 1
FCGBP Fc fragment of IgG binding protein
JCHAIN joining chain of multimeric IgA and IgM
MOCOS molybdenum cofactor sulfurase
MXI1 MAX interactor 1, dimerization protein
NNMT nicotinamide N-methyltransferase
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RPL38 ribosomal protein L38
S100P S100 calcium binding protein P
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SLURP1 secreted LY6/PLAUR domain containing 1
STC2 stanniocalcin 2
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
VAT1 vesicle amine transport 1
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
BTG3 BTG family, member 3
CDK6 cyclin-dependent kinase 6
CES1 carboxylesterase 1
CXADR coxsackie virus and adenovirus receptor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNM1L dynamin 1-like
DST dystonin
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA6 integrin, alpha 6
KIF14 kinesin family member 14
KRT19 keratin 19, type I
MACF1 microtubule-actin crosslinking factor 1
MSMB microseminoprotein, beta-
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NFIB nuclear factor I/B
OLFM1 olfactomedin 1
TACSTD2 tumor-associated calcium signal transducer 2
TGFBR3 transforming growth factor, beta receptor III
TOX3 TOX high mobility group box family member 3
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb