BRD-K06569345_HG-5-88-01_MCF10A_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K06569345_HG-5-88-01_MCF10A_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BASP1 brain abundant, membrane attached signal protein 1
BLNK B-cell linker
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CDK19 cyclin-dependent kinase 19
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFD complement factor D (adipsin)
CLU clusterin
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSTA cystatin A (stefin A)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
EFS embryonal Fyn-associated substrate
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GATA3 GATA binding protein 3
HMOX1 heme oxygenase 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
JUP junction plakoglobin
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT7 keratin 7, type II
LGALS3 lectin, galactoside-binding, soluble, 3
LTF lactotransferrin
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
METTL7A methyltransferase like 7A
MYO6 myosin VI
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPDC1 neural proliferation, differentiation and control, 1
NPIPB3 nuclear pore complex interacting protein family, member B3
PENK proenkephalin
PERP PERP, TP53 apoptosis effector
PPL periplakin
PRAME preferentially expressed antigen in melanoma
RPL39L ribosomal protein L39-like
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SMC1A structural maintenance of chromosomes 1A
SVIL supervillin
SYNE2 spectrin repeat containing, nuclear envelope 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1
TRIM29 tripartite motif containing 29
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ATF5 activating transcription factor 5
BCL2A1 BCL2-related protein A1
CXCL14 chemokine (C-X-C motif) ligand 14
DLC1 DLC1 Rho GTPase activating protein
EDNRB endothelin receptor type B
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM46A family with sequence similarity 46, member A
HBB hemoglobin, beta
HBEGF heparin-binding EGF-like growth factor
IL13RA2 interleukin 13 receptor, alpha 2
KLF10 Kruppel-like factor 10
MAPK13 mitogen-activated protein kinase 13
MEF2C myocyte enhancer factor 2C
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MYLK myosin light chain kinase
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PLK2 polo-like kinase 2
QDPR quinoid dihydropteridine reductase
RBP1 retinol binding protein 1, cellular
RFTN1 raftlin, lipid raft linker 1
RGS10 regulator of G-protein signaling 10
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SCG5 secretogranin V
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase