BRD-K06569345_HG-5-88-01_HME1_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

147 genes differentially expressed following the BRD-K06569345_HG-5-88-01_HME1_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
ADAM28 ADAM metallopeptidase domain 28
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA4 annexin A4
ASS1 argininosuccinate synthase 1
BLNK B-cell linker
C14ORF132 chromosome 14 open reading frame 132
C1R complement component 1, r subcomponent
C1RL complement component 1, r subcomponent-like
C1S complement component 1, s subcomponent
CALD1 caldesmon 1
CCDC92 coiled-coil domain containing 92
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFD complement factor D (adipsin)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLEC7A C-type lectin domain family 7, member A
COL18A1 collagen, type XVIII, alpha 1
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DSE dermatan sulfate epimerase
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EGFR epidermal growth factor receptor
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F13A1 coagulation factor XIII, A1 polypeptide
F2RL1 coagulation factor II (thrombin) receptor-like 1
FBLN1 fibulin 1
FOXN3 forkhead box N3
FTH1 ferritin, heavy polypeptide 1
FZD7 frizzled class receptor 7
GBP2 guanylate binding protein 2, interferon-inducible
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPNMB glycoprotein (transmembrane) nmb
GREM1 gremlin 1, DAN family BMP antagonist
GRN granulin
GSTM3 glutathione S-transferase mu 3 (brain)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HBB hemoglobin, beta
IDS iduronate 2-sulfatase
IGF1R insulin-like growth factor 1 receptor
IGFBP7 insulin-like growth factor binding protein 7
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGAV integrin, alpha V
JAG1 jagged 1
LAMP2 lysosomal-associated membrane protein 2
LEFTY1 left-right determination factor 1
LINC00341 long intergenic non-protein coding RNA 341
LOXL1 lysyl oxidase-like 1
LY75 lymphocyte antigen 75
MMP12 matrix metallopeptidase 12
MXI1 MAX interactor 1, dimerization protein
MXRA5 matrix-remodelling associated 5
MXRA7 matrix-remodelling associated 7
MXRA8 matrix-remodelling associated 8
N4BP2L1 NEDD4 binding protein 2-like 1
NDRG1 N-myc downstream regulated 1
NKG7 natural killer cell granule protein 7
NOV nephroblastoma overexpressed
NUAK1 NUAK family, SNF1-like kinase, 1
NUPR1 nuclear protein, transcriptional regulator, 1
PALLD palladin, cytoskeletal associated protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PLEKHA5 pleckstrin homology domain containing, family A member 5
RNF144A ring finger protein 144A
RRAGD Ras-related GTP binding D
SCGB2A1 secretoglobin, family 2A, member 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SHANK2 SH3 and multiple ankyrin repeat domains 2
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
SPON2 spondin 2, extracellular matrix protein
SQSTM1 sequestosome 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STON1 stonin 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TGIF1 TGFB-induced factor homeobox 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPST2 tyrosylprotein sulfotransferase 2
TSC22D1 TSC22 domain family, member 1
VAT1 vesicle amine transport 1
WDTC1 WD and tetratricopeptide repeats 1
ZMIZ1 zinc finger, MIZ-type containing 1

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL3 acyl-CoA synthetase long-chain family member 3
AURKA aurora kinase A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CDC42 cell division cycle 42
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
CENPF centromere protein F, 350/400kDa
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
CSE1L CSE1 chromosome segregation 1-like (yeast)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EBP emopamil binding protein (sterol isomerase)
ELOVL6 ELOVL fatty acid elongase 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP7 fatty acid binding protein 7, brain
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GINS2 GINS complex subunit 2 (Psf2 homolog)
HIST1H4C histone cluster 1, H4c
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMMR hyaluronan-mediated motility receptor (RHAMM)
IDI1 isopentenyl-diphosphate delta isomerase 1
IFRD2 interferon-related developmental regulator 2
KIAA0101 KIAA0101
KIF20A kinesin family member 20A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LDLR low density lipoprotein receptor
MRPL12 mitochondrial ribosomal protein L12
MSMO1 methylsterol monooxygenase 1
MYCBP MYC binding protein
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NUSAP1 nucleolar and spindle associated protein 1
PCNA proliferating cell nuclear antigen
PLK1 polo-like kinase 1
RAD51C RAD51 paralog C
RPA3 replication protein A3, 14kDa
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SRSF7 serine/arginine-rich splicing factor 7
SUB1 SUB1 homolog (S. cerevisiae)
TACC3 transforming, acidic coiled-coil containing protein 3
TPX2 TPX2, microtubule-associated
TRA2B transformer 2 beta homolog (Drosophila)
TSPAN13 tetraspanin 13
UBE2S ubiquitin-conjugating enzyme E2S
VBP1 von Hippel-Lindau binding protein 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZWINT ZW10 interacting kinetochore protein