BRD-K06476055_-666_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-K06476055_-666_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALCAM activated leukocyte cell adhesion molecule
CCND1 cyclin D1
FADS1 fatty acid desaturase 1
FUCA1 fucosidase, alpha-L- 1, tissue
GOLGA8A golgin A8 family, member A
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
MARCKSL1 MARCKS-like 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
ARMCX1 armadillo repeat containing, X-linked 1
BPHL biphenyl hydrolase-like (serine hydrolase)
CD93 CD93 molecule
G0S2 G0/G1 switch 2
GPM6B glycoprotein M6B
HIST1H4C histone cluster 1, H4c
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
MGP matrix Gla protein
NID1 nidogen 1
PLN phospholamban
SFRP4 secreted frizzled-related protein 4
SULF1 sulfatase 1