BRD-K06405410_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K06405410_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALOX5 arachidonate 5-lipoxygenase
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CCND2 cyclin D2
CCNG2 cyclin G2
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL9A2 collagen, type IX, alpha 2
CPM carboxypeptidase M
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FRZB frizzled-related protein
H1F0 H1 histone family, member 0
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HYOU1 hypoxia up-regulated 1
KDM3A lysine (K)-specific demethylase 3A
MEF2C myocyte enhancer factor 2C
MEST mesoderm specific transcript
MFSD10 major facilitator superfamily domain containing 10
MT1M metallothionein 1M
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PLIN2 perilipin 2
PLXNB2 plexin B2
RTN1 reticulon 1
S100P S100 calcium binding protein P
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SNX13 sorting nexin 13
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TFPI2 tissue factor pathway inhibitor 2
TMEM45A transmembrane protein 45A
TPBG trophoblast glycoprotein
TSPYL5 TSPY-like 5
VAMP8 vesicle-associated membrane protein 8
VEGFA vascular endothelial growth factor A
YBX3 Y box binding protein 3

decreased expression

Symbol Name
CD59 CD59 molecule, complement regulatory protein
CLU clusterin
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HP haptoglobin
IGFBP7 insulin-like growth factor binding protein 7
KIAA0125 KIAA0125
NRN1 neuritin 1
PHYH phytanoyl-CoA 2-hydroxylase
THBS1 thrombospondin 1
VSNL1 visinin-like 1