BRD-K06234293_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K06234293_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
APOD apolipoprotein D
AREG amphiregulin
ARHGAP29 Rho GTPase activating protein 29
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BLNK B-cell linker
CCL5 chemokine (C-C motif) ligand 5
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
COLEC12 collectin sub-family member 12
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CXCL10 chemokine (C-X-C motif) ligand 10
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DST dystonin
DUSP4 dual specificity phosphatase 4
EPN2 epsin 2
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
GEM GTP binding protein overexpressed in skeletal muscle
GREM1 gremlin 1, DAN family BMP antagonist
LOC100272216 uncharacterized LOC100272216
MAP7 microtubule-associated protein 7
MEIS1 Meis homeobox 1
MTSS1 metastasis suppressor 1
NIT1 nitrilase 1
NPTX2 neuronal pentraxin II
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAI14 retinoic acid induced 14
REEP1 receptor accessory protein 1
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASE6 ribonuclease, RNase A family, k6
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SH3BGRL SH3 domain binding glutamate-rich protein like
SNX7 sorting nexin 7
TRIM2 tripartite motif containing 2
TXNIP thioredoxin interacting protein
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WSB1 WD repeat and SOCS box containing 1
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK6 cyclin-dependent kinase 6
CXCL8 chemokine (C-X-C motif) ligand 8
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GLS glutaminase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
JUNB jun B proto-oncogene
MYC v-myc avian myelocytomatosis viral oncogene homolog
NUP98 nucleoporin 98kDa
ODC1 ornithine decarboxylase 1
PRKCD protein kinase C, delta
PSAT1 phosphoserine aminotransferase 1
S100A2 S100 calcium binding protein A2
SCARB1 scavenger receptor class B, member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC35F2 solute carrier family 35, member F2
UBE2E3 ubiquitin-conjugating enzyme E2E 3