BRD-K06198550_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

66 genes differentially expressed following the BRD-K06198550_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
ARG2 arginase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
AXIN1 axin 1
BEX1 brain expressed, X-linked 1
CBS cystathionine-beta-synthase
CD24 CD24 molecule
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN3 claudin 3
CRABP2 cellular retinoic acid binding protein 2
CTBP2 C-terminal binding protein 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
FADS1 fatty acid desaturase 1
FGFR2 fibroblast growth factor receptor 2
GATA6 GATA binding protein 6
GDF15 growth differentiation factor 15
GJA1 gap junction protein, alpha 1, 43kDa
GSDMB gasdermin B
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMOX1 heme oxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
ISYNA1 inositol-3-phosphate synthase 1
KLF4 Kruppel-like factor 4 (gut)
LGALS4 lectin, galactoside-binding, soluble, 4
LXN latexin
MDK midkine (neurite growth-promoting factor 2)
PDZK1IP1 PDZK1 interacting protein 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PYCARD PYD and CARD domain containing
QPCT glutaminyl-peptide cyclotransferase
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC38A2 solute carrier family 38, member 2
STC2 stanniocalcin 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TRIM22 tripartite motif containing 22
VAT1 vesicle amine transport 1
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase
ZNF217 zinc finger protein 217

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANGPT1 angiopoietin 1
CSRP2 cysteine and glycine-rich protein 2
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS2 dehydrogenase/reductase (SDR family) member 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GNAS GNAS complex locus
GRWD1 glutamate-rich WD repeat containing 1
H2AFX H2A histone family, member X
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KIF14 kinesin family member 14
ODC1 ornithine decarboxylase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
TIMP3 TIMP metallopeptidase inhibitor 3
ZWILCH zwilch kinetochore protein