BRD-K05870596_XMD-1499_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K05870596_XMD-1499_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT1 acetyl-CoA acetyltransferase 1
AK1 adenylate kinase 1
AQP3 aquaporin 3 (Gill blood group)
ASNS asparagine synthetase (glutamine-hydrolyzing)
AUTS2 autism susceptibility candidate 2
BAD BCL2-associated agonist of cell death
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DACH1 dachshund family transcription factor 1
FAR2 fatty acyl CoA reductase 2
FBP1 fructose-1,6-bisphosphatase 1
FHL1 four and a half LIM domains 1
GDF15 growth differentiation factor 15
GSTP1 glutathione S-transferase pi 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KLF4 Kruppel-like factor 4 (gut)
NGRN neugrin, neurite outgrowth associated
NUPR1 nuclear protein, transcriptional regulator, 1
PHGDH phosphoglycerate dehydrogenase
PIP prolactin-induced protein
PSAT1 phosphoserine aminotransferase 1
PYCR1 pyrroline-5-carboxylate reductase 1
QPCT glutaminyl-peptide cyclotransferase
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SFTPB surfactant protein B
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SORBS2 sorbin and SH3 domain containing 2
SSBP2 single-stranded DNA binding protein 2
TMEM45A transmembrane protein 45A
TMEM47 transmembrane protein 47
VCAN versican

decreased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
ATG3 autophagy related 3
BST2 bone marrow stromal cell antigen 2
CADM1 cell adhesion molecule 1
CD200 CD200 molecule
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CHN1 chimerin 1
COL11A1 collagen, type XI, alpha 1
CRABP1 cellular retinoic acid binding protein 1
CRELD2 cysteine-rich with EGF-like domains 2
CXCL10 chemokine (C-X-C motif) ligand 10
CYCS cytochrome c, somatic
DLK1 delta-like 1 homolog (Drosophila)
DUSP5 dual specificity phosphatase 5
FLNA filamin A, alpha
GBP2 guanylate binding protein 2, interferon-inducible
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPRC5B G protein-coupled receptor, class C, group 5, member B
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HEPH hephaestin
IGFBP5 insulin-like growth factor binding protein 5
IQGAP1 IQ motif containing GTPase activating protein 1
ISG15 ISG15 ubiquitin-like modifier
JUND jun D proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
KLK6 kallikrein-related peptidase 6
KLK8 kallikrein-related peptidase 8
LAMP1 lysosomal-associated membrane protein 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MDFIC MyoD family inhibitor domain containing
NRCAM neuronal cell adhesion molecule
PEG10 paternally expressed 10
PLIN2 perilipin 2
PTBP1 polypyrimidine tract binding protein 1
PTCH1 patched 1
SCG2 secretogranin II
SPON1 spondin 1, extracellular matrix protein
SST somatostatin
STAR steroidogenic acute regulatory protein
TNS3 tensin 3
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2
TSPAN7 tetraspanin 7
ZFP36L2 ZFP36 ring finger protein-like 2