BRD-K05804044_AZ-628_HT29_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

166 genes differentially expressed following the BRD-K05804044_AZ-628_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
AFF1 AF4/FMR2 family, member 1
AGR2 anterior gradient 2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKRD36B ankyrin repeat domain 36B
ANXA9 annexin A9
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP9A ATPase, class II, type 9A
AZU1 azurocidin 1
BST2 bone marrow stromal cell antigen 2
C10ORF10 chromosome 10 open reading frame 10
C2CD5 C2 calcium-dependent domain containing 5
CA12 carbonic anhydrase XII
CAPG capping protein (actin filament), gelsolin-like
CCDC92 coiled-coil domain containing 92
CCNG2 cyclin G2
CES1 carboxylesterase 1
COL4A5 collagen, type IV, alpha 5
CTSA cathepsin A
CTSG cathepsin G
DEPTOR DEP domain containing MTOR-interacting protein
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ERBB3 erb-b2 receptor tyrosine kinase 3
ERGIC3 ERGIC and golgi 3
FAM63A family with sequence similarity 63, member A
FCGBP Fc fragment of IgG binding protein
FOXO4 forkhead box O4
FZD2 frizzled class receptor 2
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GAS6 growth arrest-specific 6
GLUL glutamate-ammonia ligase
GPATCH8 G patch domain containing 8
GRN granulin
GSN gelsolin
HES1 hes family bHLH transcription factor 1
HLA-E major histocompatibility complex, class I, E
HOOK2 hook microtubule-tethering protein 2
HP haptoglobin
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IDS iduronate 2-sulfatase
IGFBP3 insulin-like growth factor binding protein 3
IRF9 interferon regulatory factor 9
ITM2A integral membrane protein 2A
LCN2 lipocalin 2
LGALS1 lectin, galactoside-binding, soluble, 1
LINC00342 long intergenic non-protein coding RNA 342
LOX lysyl oxidase
LTF lactotransferrin
MLPH melanophilin
MVP major vault protein
NBPF10 neuroblastoma breakpoint family, member 10
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NOTCH2NL notch 2 N-terminal like
NPC2 Niemann-Pick disease, type C2
NPIPB3 nuclear pore complex interacting protein family, member B3
NUPR1 nuclear protein, transcriptional regulator, 1
OBSL1 obscurin-like 1
OPTN optineurin
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PER3 period circadian clock 3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAB31 RAB31, member RAS oncogene family
RSRP1 arginine/serine-rich protein 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB2A1 secretoglobin, family 2A, member 1
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SESN1 sestrin 1
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SH3BGRL SH3 domain binding glutamate-rich protein like
SIX1 SIX homeobox 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SOX4 SRY (sex determining region Y)-box 4
TRA2A transformer 2 alpha homolog (Drosophila)
TTC3 tetratricopeptide repeat domain 3
TUBA1A tubulin, alpha 1a
TXNIP thioredoxin interacting protein
WDTC1 WD and tetratricopeptide repeats 1
WFDC2 WAP four-disulfide core domain 2
WNT5A wingless-type MMTV integration site family, member 5A
YPEL5 yippee-like 5 (Drosophila)
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZIC1 Zic family member 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMD1 adenosylmethionine decarboxylase 1
AXIN1 axin 1
BAG2 BCL2-associated athanogene 2
C7 complement component 7
CALB1 calbindin 1, 28kDa
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CD320 CD320 molecule
COTL1 coactosin-like F-actin binding protein 1
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DPH2 DPH2 homolog (S. cerevisiae)
DPT dermatopontin
DUSP6 dual specificity phosphatase 6
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EREG epiregulin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FASN fatty acid synthase
FGFBP1 fibroblast growth factor binding protein 1
FKBP11 FK506 binding protein 11, 19 kDa
FOSL1 FOS-like antigen 1
FST follistatin
GAL galanin/GMAP prepropeptide
GLS glutaminase
GNLY granulysin
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GZMK granzyme K (granzyme 3; tryptase II)
HBEGF heparin-binding EGF-like growth factor
HK1 hexokinase 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
INPP1 inositol polyphosphate-1-phosphatase
ITGA6 integrin, alpha 6
KRT6A keratin 6A, type II
LCK LCK proto-oncogene, Src family tyrosine kinase
LPL lipoprotein lipase
MALL mal, T-cell differentiation protein-like
MCM4 minichromosome maintenance complex component 4
MRPS12 mitochondrial ribosomal protein S12
MTCL1 microtubule crosslinking factor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
NPM3 nucleophosmin/nucleoplasmin 3
ODC1 ornithine decarboxylase 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PHLDA1 pleckstrin homology-like domain, family A, member 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPIF peptidylprolyl isomerase F
PRF1 perforin 1 (pore forming protein)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTHLH parathyroid hormone-like hormone
QDPR quinoid dihydropteridine reductase
SEH1L SEH1-like (S. cerevisiae)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SPRR1A small proline-rich protein 1A
SRM spermidine synthase
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TFRC transferrin receptor
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TSPAN4 tetraspanin 4
UBE2S ubiquitin-conjugating enzyme E2S
UBE3C ubiquitin protein ligase E3C
UPP1 uridine phosphorylase 1
WSB2 WD repeat and SOCS box containing 2
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing